Evidence map›Paper›PMID 39589463›Full record

ReviewDigestive diseases and sciences2025

Diagnosis and Treatment of Choledochal Cysts: A Comprehensive Review with a Focus on Choledochocele.

Carlo Ciccioli, Stefano Mazza, Andrea Sorge, Francesca Torello Viera, Aurelio Mauro, Alessandro Vanoli, Marco Bardone, Davide Scalvini, Laura Rovedatti, Lodovica Pozzi and 7 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Carlo CiccioliSection of Gastroenterology and Hepatology, Dipartimento Di Promozione Della Salute, Materno Infantile, Medicina Interna e Specialistica Di Eccellenza (PROMISE), University of Palermo, 90127, Palermo, Italy.
Stefano MazzaGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy. st.mazza@smatteo.pv.it.ORCID http://orcid.org/0000-0002-9068-3209
Andrea SorgeDepartment of Pathophysiology and Transplantation, Università Degli Studi Di Milano, Milan, Italy.ORCID http://orcid.org/0000-0002-0285-9949
Francesca Torello VieraGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Aurelio MauroGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.ORCID http://orcid.org/0000-0002-8475-5464
Alessandro VanoliUnit of Anatomic Pathology, Department of Molecular Medicine, University of Pavia, 27100, Pavia, Italy.
Marco BardoneGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Davide ScalviniGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.ORCID http://orcid.org/0009-0002-7051-5432
Laura RovedattiGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Lodovica PozziGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Elena StradaGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Simona AgazziGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Letizia VeroneseGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Chiara BarteselliGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Carmelo SgarlataGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Valentina RavettaGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Andrea AnderloniGastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.ORCID http://orcid.org/0000-0002-1021-0031

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Choledochal cysts (CCs) are cystic dilations of intrahepatic and/or extrahepatic bile ducts. Around 80% of CCs are diagnosed within the first decade of life. These complex clinical entities are extremely rare, especially in the Western population. CCs are frequently classified according to the Todani classification. CCs may be asymptomatic or present as acute pancreatitis and/or cholangitis, biliary obstruction, or malignancy. Therefore, the diagnosis relies primarily on abdominal imaging modalities, mainly magnetic resonance cholangiopancreatography. Management is tailored based on the cyst morphology and the patient's clinical characteristics, with surveillance, surgery, and interventional endoscopy being the most frequent management options. While the surgical approach is the most frequently employed, type III CCs (also known as choledochocele) are frequently managed endoscopically, and novel endoscopic, minimally invasive treatment options are rapidly emerging.

Indexed as

Choledochal CystCholangiopancreatography, Endoscopic RetrogradeCholangiopancreatography, Magnetic ResonanceHumansAnomalous pancreaticobiliary duct unionBiliary cystsCholedochal cystsCholedochoceleManagement of choledochal cystsTodani’s classification

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.