ArticleeLife2024
Estimating dispersal rates and locating genetic ancestors with genome-wide genealogies.
Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Spatial inference of ancestor locations suggests northern refugia for canopy-forming kelps in the Pacific Northwest.The New phytologist · 2026Article
- ARGscape: a modular, interactive tool for manipulation of spatiotemporal ancestral recombination graphs.Bioinformatics (Oxford, England) · 2026Article
- Shifting Balancing Selection Underlies an Inversion Cline in Eurasian Blackcap.Ecology and evolution · 2026Article
- Using drift coefficients as a basis for inferring times, effective population sizes, and genetic adaptations.Molecular biology and evolution · 2026Article
- Likelihoods for a general class of ARGs under the SMC.Genetics · 2026Article
- The genetic architecture and spatiotemporal dynamics of adaptation across human-modified landscapes.The New phytologist · 2026Review
- The promise and challenge of spatial inference with the full ancestral recombination graph under Brownian motion.G3 (Bethesda, Md.) · 2025Article
- Article
- ARGscape: A modular, interactive tool for manipulation of spatiotemporal ancestral recombination graphs.ArXiv · 2025Article
- Inference of complex demographic history using composite likelihood based on whole-genome genealogies.bioRxiv : the preprint server for biology · 2025Article
- Robust and accurate Bayesian inference of genome-wide genealogies for hundreds of genomes.Nature genetics · 2025Article
- A comparison of 27 Arabidopsis thaliana genomes and the path toward an unbiased characterization of genetic polymorphism.Nature genetics · 2025Article
- Tsbrowse: an interactive browser for ancestral recombination graphs.Bioinformatics (Oxford, England) · 2025Article
- The genomic footprints of migration: how ancient DNA reveals our history of mobility.Genome biology · 2025Review
- Life-history trade-offs explain local adaptation inbioRxiv : the preprint server for biology · 2025Article
- A geographic history of human genetic ancestry.Science (New York, N.Y.) · 2025Article
- Likelihoods for a general class of ARGs under the SMC.bioRxiv : the preprint server for biology · 2025Article
- Inference and applications of ancestral recombination graphs.Nature reviews. Genetics · 2025Review
- Article
- Beyond genes-for-behaviour: The potential for genomics to resolve long-standing questions in avian brood parasitism.Ecology and evolution · 2024Review
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Authors and funding
2 authors.
Funding
Abstract
Spatial patterns in genetic diversity are shaped by individuals dispersing from their parents and larger-scale population movements. It has long been appreciated that these patterns of movement shape the underlying genealogies along the genome leading to geographic patterns of isolation-by-distance in contemporary population genetic data. However, extracting the enormous amount of information contained in genealogies along recombining sequences has, until recently, not been computationally feasible. Here, we capitalize on important recent advances in genome-wide gene-genealogy reconstruction and develop methods to use thousands of trees to estimate per-generation dispersal rates and to locate the genetic ancestors of a sample back through time. We take a likelihood approach in continuous space using a simple approximate model (branching Brownian motion) as our prior distribution of spatial genealogies. After testing our method with simulations we apply it to
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