Evidence map›Paper›PMID 39589128›Full record

ArticlemBio2025

Structure and identification of the native PLP synthase complex from

Angela Agnew, Ethan Humm, Kang Zhou, Robert P Gunsalus, Z Hong Zhou

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Angela AgnewDepartment of Microbiology, Immunology & Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-4926-9217
Ethan HummDepartment of Microbiology, Immunology & Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA.
Kang ZhouCalifornia NanoSystems Institute, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-3034-2808
Robert P GunsalusDepartment of Microbiology, Immunology & Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-1937-8412
Z Hong ZhouDepartment of Microbiology, Immunology & Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-8373-4717

Funding

Research Training in Cell and Molecular BiologyT32GM145388 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jorge Torres · 2022 to 2026
$5.2M
High-Resolution CryoEM Reconstruction of Large ComplexesR01GM071940 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, Z HONG · 2006 to 2025
$5.0M
UCLA Dentist-Scientist and Oral Health-Researcher Training ProgramT90DE030860 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TON-THAT, HUNG, WONG, DAVID T · 2021 to 2025
$2.1M
Direct Detection Device for atomic resolution cryoEM of macromolecular complexesS10OD018111 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2014 to 2014
$598k
HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) T90DE030860HHS | NIH | National Institute of General Medical Sciences (NIGMS) R01GM071940, T32GM145388National Science Foundation (NSF) 1911781NIDCR NIH HHS T90 DE030860NIGMS NIH HHS R01 GM071940NIGMS NIH HHS T32 GM145388NIH HHS S10 OD018111U.S. Department of Energy (DOE) DE-FC-02-372 02ER63421
6 · The paper itself

Abstract

Many protein-protein interactions behave differently in biochemically purified forms as compared to their

Indexed as

Archaeal ProteinsCryoelectron MicroscopyMethanosarcinaModels, MolecularProtein ConformationProteomicsPyridoxal PhosphateArchaeal ProteinsPyridoxal Phosphatecryo-EMcryoIDMethanosarcina acetivoransPLP synthase

Identifiers

PMID39589128
PMCPMC11708016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.