Evidence map›Paper›PMID 39588838›Full record

ArticleGut microbes

IL-17 signaling protects against

Lee C Brackman, Matthew S Jung, Emily H Green, Nikhita Joshi, Frank L Revetta, Mark S McClain, Nicholas O Markham, M Blanca Piazuelo, Holly M Scott Algood

Abstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Managing dangerous liaisons: lessons fromJournal of bacteriology · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Inflammatory factors collaboratively linkFrontiers in immunology · 2025
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lee C BrackmanDepartment of Medicine, Division of Infectious Disease, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0009-0003-2142-9658
Matthew S JungDepartment of Medicine, Division of Infectious Disease, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0009-0005-1700-4870
Emily H GreenDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0002-9542-0192
Nikhita JoshiTennessee Valley Healthcare System, Department of Veterans Affairs, Nashville, TN, USA.
Frank L RevettaDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA.
Mark S McClainDepartment of Medicine, Division of Infectious Disease, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0002-9857-4883
Nicholas O MarkhamDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0002-1348-1267
M Blanca PiazueloDepartment of Medicine, Division of Gastroenterology, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0002-0000-1324
Holly M Scott AlgoodDepartment of Medicine, Division of Infectious Disease, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0003-3735-4649

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
N-terminal acylation and sorting of Helicobacter pylori lipoproteins and their role in host response to infectionR21AI163586 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALGOOD, HOLLY MARIE SCOTT, MCCLAIN, MARK S · 2022 to 2023
$491k
Deleted in malignant brain tumors 1 (DMBT1) expression and impact on colonic dysplasiaF31CA294983 · NCI · VANDERBILT UNIVERSITY · PI Emily H Green · 2024 to 2026
$105k
The role of Th17 cytokines in H.pylori infectionI01BX000915 · VA · VETERANS HEALTH ADMINISTRATION · PI HOLLY Marie Scott ALGOOD · 2011 to 2026
–
Gastrointestinal cell type-specific signaling and C. difficile toxin pathogenesisIK2BX005699 · VA · VETERANS HEALTH ADMINISTRATION · PI Nicholas O Markham · 2022 to 2026
–
BLRD VA I01 BX000915BLRD VA IK2 BX005699NCI NIH HHS F31 CA294983NIAID NIH HHS R21 AI163586NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Helicobacter InfectionsHelicobacter pyloriInterleukin-17Receptors, Interleukin-17Signal TransductionStomach NeoplasmsAnimalsGastritisMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicTh17 CellsIl17ra protein, mouseInterleukin-17Receptors, Interleukin-17gastric cancergastritisHelicobacter pyloriInterleukin 17

Identifiers

PMID39588838
PMCPMC11639209

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.