Evidence map›Paper›PMID 39588807›Full record

ReviewMacromolecular rapid communications2024

Coacervate Droplets as Biomimetic Models for Designing Cell-Like Microreactors.

Tsvetomir Ivanov, Thao P Doan-Nguyen, Mohammed Amin Belahouane, Zhen Dai, Shoupeng Cao, Katharina Landfester, Lucas Caire da Silva

Abstract readReview
In one paragraph

Review in Macromolecular rapid communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Sequence-Modulated Active Tripeptide Condensates for Tandem Catalysis.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tsvetomir IvanovDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
Thao P Doan-NguyenDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
Mohammed Amin BelahouaneDepartment of Chemistry, McGill University, H3A 0B8, Montreal, Canada.
Zhen DaiDepartment of Chemistry, McGill University, H3A 0B8, Montreal, Canada.
Shoupeng CaoDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
Katharina LandfesterDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
Lucas Caire da SilvaDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.ORCID https://orcid.org/0000-0003-4663-3471

Funding

Alexander von Humboldt-Stiftung 3.5-CHN-1222717-HFST-PBundesministerium für Bildung und Forschung MaxSynBioFonds de recherche du Québec - Nature et technologiesMax-Planck-Gesellschaft
6 · The paper itself

Abstract

Coacervates are versatile compartments formed by liquid-liquid phase separation. Their dynamic behavior and molecularly crowded microenvironment make them ideal materials for creating cell-like systems such as synthetic cells and microreactors. Recently, combinations of synthetic and natural molecules have been exploited via simple or complex coacervation to create compartments that can be used to build hierarchical chemical systems with life-like properties. This review highlights recent advances in the design of coacervate compartments and their application as biomimetic compartments for the design of cell-like chemical reactors and cell mimicking systems. It first explores the variety of materials used for coacervation and the influence of their chemical structure on their controlled dynamic behavior. Then, the applications of coacervates as cell-like systems are reviewed, focusing on how they can be used as cell-like microreactors through their ability to sequester molecules and provide a distinct and regulatory microenvironment for chemical reactions in aqueous media.

Indexed as

BiomimeticsArtificial CellsBiomimetic MaterialsBioreactorsbio‐mimickingcatalysiscoacervatescompartmentslife‐like materials

Identifiers

PMID39588807
PMCPMC11661669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.