Evidence map›Paper›PMID 39588531›Full record

ArticleCureus2024

A Case Report on Endometriosis-Associated Intestinal Tumour Following Hysterectomy: Diagnostic Challenges and Implications for Hormone Replacement Therapy (HRT) Guidelines.

Sara Elsaadany, Ashweta Josan, Ruth Crowley, Michelle Gouldie

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sara ElsaadanyGeneral Practice, Barking, Havering and Redbridge Primary Care, London, GBR.
Ashweta JosanGeneral Practice, Barking, Havering and Redbridge Primary Care, London, GBR.
Ruth CrowleyGeneral Practice, Barking, Havering and Redbridge Primary Care, London, GBR.
Michelle GouldieGeneral Practice, Barking, Havering and Redbridge Primary Care, London, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a complex condition that is often underdiagnosed, leaving rare but serious risks such as malignant transformation overlooked in many cases. Malignant transformation, especially in extra-gynaecological sites, poses significant diagnostic and therapeutic challenges. We present a case of an endometriosis-associated intestinal tumour diagnosed in a patient with exposure to oestrogen-only hormone replacement therapy (HRT) on a background of total abdominal hysterectomy and bilateral oophorectomy performed three decades before her presentation. This case highlights the potential for malignant transformation of residual endometriotic tissue in extra-gynaecological sites, even decades following definitive surgical management, particularly in the presence of important risk factors such as obesity and prior oestrogen-only HRT.

Indexed as

bowel endometriosisendometrial associated intestinal tumourhyper-oestrogenismmerkel cell carcinoma of unknown primaryoestrogen-only hormone replacement therapytotal abdominal hysterectomy with bilateral salpingo-oophorectomy (tahbso)

Identifiers

PMID39588531
PMCPMC11586882

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.