ArticleCureus2024
Bacteriological Profiles and Antimicrobial Susceptibility Patterns Among Isolates in Tonsillitis Patients Attending a Tertiary Care Hospital.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
backgroundTonsillitis, primarily affecting children, is an inflammation of the pharyngeal tonsils caused by bacterial pathogens such as
objectiveThis research was undertaken to assess the bacterial profiles and antibiotic susceptibility patterns of isolates obtained from tonsillitis patients. MATERIALS AND
methodsThis research was undertaken in the Department of Microbiology at Krishna Institute of Medical Sciences, Krishna Hospital and Medical Research Centre, Karad, District Satara, during the period from November 2022 to November 2023. Specimen collection and processing were performed following standard guidelines. Tonsillar swabs were collected and processed for pathogen isolation and identification using Gram staining and various biochemical tests; the susceptibility to antimicrobials was tested using the Kirby-Bauer disc diffusion method on Mueller-Hinton agar in accordance with Clinical and Laboratory Standards Institute 2022 recommendations.
resultOut of 105 clinically confirmed tonsillitis cases, 93 (88.57%) were culture-positive, with three cases presenting two isolates each, resulting in a total of 96 isolates, and 12 cases (11.43%) were culture-negative. A greater prevalence was noted among male patients (56 (60.21%)), with the highest occurrence observed in the 0-20-year age group (60 (64.51%)). Among the 96 isolates, 52 (54.16%) were Gram-negative and 44 (45.83%) were Gram-positive. The predominant isolate identified was
conclusionAmong 105 clinically confirmed tonsillitis cases, 93 were culture-positive, resulting in 96 isolates.
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