Evidence map›Paper›PMID 39588425›Full record

ArticleCureus2024

Evaluating Autism Risk Factors and Their Impact on Children in Thi-Qar, Iraq.

Adnan M Al-Rikabi, Amin T Atya, Naama J Gazar, Mohammed S Almaliki, Huda M Omran

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adnan M Al-RikabiPediatrics, Medical College, University of Thi-Qar, Thi-Qar, IRQ.
Amin T AtyaPediatrics, Medical College, University of Thi-Qar, Thi-Qar, IRQ.
Naama J GazarPediatrics, Bint Al-Huda Maternity and Children Teaching Hospital ,Thi-Qar Health Directorate, Thi-Qar, IRQ.
Mohammed S AlmalikiPediatrics, American Mission Hospital, Manama, BHR.
Huda M OmranGenetics: Molecular Genetics, Pulse Health Training Center, Al Jenan Medical Center, Manama, BHR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Autism is a neurodevelopmental disorder marked by difficulties in social communication, language, restricted interests, and repetitive behaviors. Aim This study aims to identify potential risk factors for autism among children and assess their effects on early developmental skills. Methods A case-control study was conducted from September 2022 to September 2023, involving 298 children with autism (265 boys, 33 girls) aged four to 12 from the Thi-Qar Autistic Children Center and private clinics in Iraq. A control group of 300 children (150 boys, 150 girls) was also included. Data were collected through a specialized questionnaire covering demographics, neonatal history (e.g., jaundice, birth asphyxia), parental age, and developmental skills (motor milestones, speech, handwriting). Results Among the 298 children with autism enrolled, 265 (89%) were boys and 33 (11%) were girls. Children with autism had a positive family history of autism in 207 (69%) compared to 15 (5%) in the control group (p < 0.001). Paternal age over 35 years at the time of birth was noted in 159 (53%) versus 75 (25%) for the control group (p < 0.001). Maternal age over 35 showed no significant difference (p = 0.23). Hypoxia at birth was present in 153 (51%) children with autism compared to 45 (15%) in the control group (p = 0.001). Significant developmental delays were observed, including speech defects in 210 (70%) children with autism versus 15 (5%) in controls (p < 0.001). In terms of handwriting, 240 (80%) children with autism demonstrated acceptable handwriting skills, while 60 (20%) did not, compared to 264 (88%) in the control group who achieved handwriting skills, resulting in a p-value of 0.23. Conclusions The findings indicate that boys are more affected than girls, with significant risk factors including family history, paternal age, and neonatal birth asphyxia. Children with autism demonstrated marked delays in motor skills and speech defects, emphasizing the need for early detection and intervention.

Indexed as

autismchildrendevelopmental delaysrisk factorsthi-qar

Identifiers

PMID39588425
PMCPMC11588032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.