Evidence map›Paper›PMID 39588228›Full record

ArticleClinical, cosmetic and investigational dermatology2024

Novel Prognostic Markers for Skin Cutaneous Melanoma.

Yi Zhang, Ansheng Xie, Di Wang, Weiwei Deng

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi Zhang *Department of Dermatology, the Affiliated Hospital of Inner Mongolia Medical University, Hohhot, People's Republic of China.
Ansheng Xie *Dermatology Hospital of Southern Medical University, Zhou Guang, People's Republic of China.
Di WangDermatology Hospital of Southern Medical University, Zhou Guang, People's Republic of China.
Weiwei DengDermatology Hospital of Southern Medical University, Zhou Guang, People's Republic of China.ORCID 0000-0002-6425-956X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Skin cutaneous melanoma (SKCM) ranks among the most prevalent malignant tumors, highlighting the significance of identifying new research targets. In this study, our objective was to pinpoint pivotal genes implicated in SKCM pathogenesis and ascertain their potential as prognostic biomarkers. Methods: Leveraging data from 1809 normal skin samples and 471 SKCM samples, we identified differentially expressed genes (DEGs). Using a comprehensive suite of bioinformatic analyses, including weighted gene co-expression network analysis (WGCNA), we elucidated the functions of these DEGs and singled out hub genes. Cox analyses and overall survival analyses underscored that elevated expression of these genes correlated with more favorable prognoses. Results: Ultimately, we identified five genes ( Conclusion: In summary, our study identified a series of potential prognostic genes in melanoma and verified the functional role of

Indexed as

CCR8IL4I1prognostic biomarkersskin cutaneous melanomaZNF80

Identifiers

PMID39588228
PMCPMC11586483

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.