Evidence map›Paper›PMID 39588168›Full record

ArticleSAGE open medical case reports2024

May-Hegglin anomaly associated nephropathy: Case series.

Matthew D Nguyen, Gayathri Dileep, Marrey Quizon, Vu Nguyen, Arif Demerci, Ramy Hanna

Erratum issuedAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in SAGE open medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Matthew D NguyenDivision of Nephrology, Hypertension and Transplant Nephrology, University of California, Irvine, CA, USA.ORCID https://orcid.org/0000-0002-6517-041X
Gayathri DileepDivision of Nephrology, Hypertension and Transplant Nephrology, University of California, Irvine, CA, USA.
Marrey QuizonDivision of Nephrology, Hypertension and Transplant Nephrology, University of California, Irvine, CA, USA.
Vu NguyenDivision of Nephrology, Hypertension and Transplant Nephrology, University of California, Irvine, CA, USA.
Arif DemerciDivision of Nephrology, Hypertension and Transplant Nephrology, University of California, Irvine, CA, USA.ORCID https://orcid.org/0009-0000-9423-0867
Ramy HannaDivision of Nephrology, Hypertension and Transplant Nephrology, University of California, Irvine, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

May-Hegglin anomaly (MHA) is a rare autosomal dominant disease associated with a mutation in the MYH-9 gene. It is characterized by macrothrombocytopenia and neutrophils with abnormal cytoplasmic inclusions. Clinical features of this disease include hearing loss, early cataracts, and renal failure. We present two interesting cases of renal injury attributed to MHA. The first is a 52-year-old Hispanic female with MHA-associated nephropathy and thrombocytopenia complicated by Stage 3 chronic kidney disease (CKD) and hypothyroidism. She was found to have a pathogenic MYH-9 heterozygous mutation with associated clinical characteristics. Due to her thrombocytopenia from MHA, patient is not a candidate for kidney biopsy. She has been treated with SGLT-2 inhibitors, Angiotensin Receptor Blockers (ARBs) for managing her Stage 3b CKD and Synthroid

Indexed as

chronic kidney diseaseMay-Hegglin anomalyMyh9Myh9-RDnephropathythrombocytopenia

Identifiers

PMID39588168
PMCPMC11587175

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.