Evidence map›Paper›PMID 39587862›Full record

ArticleAutism research : official journal of the International Society for Autism Research2025

Assessing the causal association between celiac disease and autism spectrum disorder: A two-sample Mendelian randomization approach.

Abiodun Fatoba, Claire Simpson

Abstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abiodun FatobaDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Centers, Memphis, Tennessee, USA.ORCID 0000-0003-2055-7036
Claire SimpsonDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Centers, Memphis, Tennessee, USA.ORCID 0000-0003-2244-7690

Funding

The CHARGE Study Phase II: A Multifactorial Approach to Autism EtiologyR01ES031701 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BENNETT, DEBORAH HALL, HERTZ-PICCIOTTO, IRVA · 2020 to 2025
$8.3M
NIEHS NIH HHS R01 ES031701NIEHS NIH HHS R01ES031701
6 · The paper itself

Abstract

The association between celiac disease (CD) and autism spectrum disorder (ASD) remains inconclusive. Reports from different observational studies have become controversial, necessitating exploration of the causal relationship between CD and ASD. To assess true causality, this study used a two-sample Mendelian randomization (MR) analysis to determine the causal association between CD and ASD. Summary-level data from a genome-wide association study (GWAS) of the European population were used to select instrument variables (IVs) at genome-wide significance (p < 5 × 10

Indexed as

Autism Spectrum DisorderCeliac DiseaseMendelian Randomization AnalysisCausalityGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansPolymorphism, Single Nucleotideautism spectrum disorderceliac diseaseGWASinstrument‐variablesMendelian randomizationsingle nucleotide polymorphisms

Identifiers

PMID39587862
PMCPMC11849517

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.