Evidence map›Paper›PMID 39587762›Full record

ArticleMagnetic resonance in medicine2025

3D MR elastography at 0.55 T: Concomitant field effects and feasibility.

Omar Isam Darwish, Pierluigi Di Cio, Ralph Sinkus, Radhouene Neji

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Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. MR Elastography Using the Gravitational Transducer.Sensors (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Omar Isam DarwishResearch Department of Imaging Physics and Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.ORCID 0000-0003-4747-9007
Pierluigi Di CioResearch Department of Imaging Physics and Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Ralph SinkusResearch Department of Imaging Physics and Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Radhouene NejiResearch Department of Imaging Physics and Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Funding

CRUK C7893/A26233Siemens HealthineersWellcome/EPSRC Centre for Medical Engineering WT203148/Z/16/ZWellcome Trust
6 · The paper itself

Abstract

purposeTo demonstrate the feasibility of hepatic 3D MR elastography (MRE) at 0.55 T in healthy volunteers using Hadamard encoding and to study the effects of concomitant fields in the domain of MRE in general.

methodsConcomitant field effects in MRE are assessed using a Taylor series expansion and an encoding scheme is proposed to study the corresponding effects on 3D MRE at 0.55 T in numerical simulations and in phantom experiments. In addition, five healthy volunteers were enrolled and scanned at 60 Hz mechanical excitation with a Hadamard-encoded 3D MRE sequence at 0.55 T and were also scanned with a reference 3D MRE sequence at 3 T for comparison. The retrieved biomechanical parameters were the magnitude of the complex shear modulus (|G*|), the shear wave speed (Cs), and the loss modulus (G″). Comparison of apparent SNR between 3 T and 0.55 T was performed.

resultsTheoretical analysis, numerical simulations and phantom experiments demonstrated that the effects of concomitant fields in 3D MRE at 0.55 T are negligible. In the healthy volunteer experiments, the mean values of |G*|, Cs, and G″ in the liver were 2.1 ± 0.3 kPa, 1.5 ± 0.1 m/s, and 0.8 ± 0.1 kPa at 0.55 T, respectively, and 2.0 ± 0.2 kPa, 1.5 ± 0.1 m/s, and 0.9 ± 0.1 kPa at 3 T, respectively. Bland-Altman analysis demonstrated good agreement between the biomechanical parameters retrieved at 0.55 T and 3 T. A 2.1-fold relative apparent SNR decrease was observed in 3D MRE at 0.55 T in comparison with 3 T.

conclusionHepatic 3D MRE is feasible at 0.55 T, showing promising initial results in healthy volunteers.

Indexed as

Elasticity Imaging TechniquesImaging, Three-DimensionalLiverMagnetic Resonance ImagingAdultAlgorithmsComputer SimulationFeasibility StudiesFemaleHealthy VolunteersHumansMalePhantoms, ImagingSignal-To-Noise Ratioconcomitant fieldsHadamard encodingliverlow field MRMR elastography

Identifiers

PMID39587762
PMCPMC11782726

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.