ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2024
[Analysis of multidrug resistance gene locus mutations and clinical significance in children with
Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Association between 23S rRNA gene positivity and clinical characteristics in patients with mycoplasma pneumoniae pneumonia.BMC pediatrics · 2026Article
- Construction of a risk prediction model for severe community-acquired pneumonia in children in Qinghai region.BMJ paediatrics open · 2026Review
- Clinical correlation of A2063G gene mutation in mycoplasma pneumoniae pneumonia in children: a retrospective analysis.Frontiers in pediatrics · 2026Article
- AgeFrontiers in pediatrics · 2026Article
- Age and hypoalbuminemia independently predict pulmonary consolidation in children with 23S rRNA A2063G-mutantFrontiers in pediatrics · 2026Article
- Macrolide-resistant Mycoplasma pneumoniae pneumonia in Chinese children: a retrospective study of clinical features and prognosis.Italian journal of pediatrics · 2025Article
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Authors and funding
3 authors.
Funding
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Abstract
objectivesTo detect multidrug resistance gene locus mutations in children with
methodsA retrospective analysis was conducted on the clinical data of 2 899 children with
resultsAmong the 2 899 children, 885 cases (30.53%) had mutations in the 23SrRNA resistance gene, including 884 cases with the A2063G mutation and 1 case with the A2064G mutation. In children with 23SrRNA resistance gene mutations, treatment with doxycycline or ofloxacin was more effective than with azithromycin or clarithromycin, and doxycycline was more effective than ofloxacin (
conclusionsAge, extrapulmonary infections, lung consolidation, duration of fever, length of hospitalization, and CRP levels are closely related to 23SrRNA resistance gene locus mutations. Detecting multidrug resistance gene locus mutations in children with
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