ArticleEuropean journal of medical research2024
Triglyceride levels are associated with 30-day mortality in intensive care patients: a retrospective analysis in the MIMIC-IV database.
Article in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical lipidomics in bacterial sepsis: a systematic review of serum and plasma evaluations.Metabolomics : Official journal of the Metabolomic Society · 2026Pooled it
- Lower triglyceride-cholesterol-body weight index is independently associated with increased in-hospital complication risk: a large multicenter real-world study.Lipids in health and disease · 2026Observational
- The sicker the patient, the higher the mortality.Critical care (London, England) · 2025Article
- Propofol-related biological alterations and incidence of propofol infusion syndrome in status epilepticus: a 10-year cohort study.Frontiers in neurology · 2025Article
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Abstract
backgroundPrevious studies suggest that septic patients often have elevated triglyceride levels due to various factors, and higher levels may indicate a poorer prognosis. However, few studies have investigated whether lower triglycerides are associated with a better prognosis.
methodsThe Medical Information Mart for Intensive Care IV (MIMIC-IV) database provided all the data. To assess the association between triglycerides and prognosis, we used logistic regression analysis (LR), least absolute shrinkage and selection operator (LASSO) and Cox proportional hazards models.
resultsInclusion criteria were met by a total of 804 patients with a mean triglyceride of 103 mg/dL. We found that patients had a higher risk of 30-day ICU mortality when triglycerides were in the second quartile (74-103 mg/dL). Interestingly, this group of patients seems to benefit more from the use of atorvastatin.
conclusionOur study showed that septic patients with triglyceride levels in the second quartile (74-103 mg/dL) have a higher 30-day ICU mortality rate compared to those with triglyceride levels in other quartiles.
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