Evidence map›Paper›PMID 39587629›Full record

ArticleMolecular neurodegeneration2024

A novel AAV Vector for gene therapy of RPE-related retinal degenerative diseases via intravitreal delivery.

Yajun Gong, Xianyu Huang, Tianxiang Tu, Cenfeng Chu, Chunrui Xian, Yushun Yuan, Xin Fu, Ruobi Li, Guisheng Zhong, Xiaolai Zhou

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular neurodegeneration, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yajun Gong *State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, 54 Xianlie South Rd, Guangzhou, 510060, China.
Xianyu Huang *Shanghai EmayGene Biotech Co. Ltd, Shanghai, 201203, China.
Tianxiang TuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, 54 Xianlie South Rd, Guangzhou, 510060, China.
Cenfeng ChuiHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Chunrui XianiHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Yushun YuanShanghai EmayGene Biotech Co. Ltd, Shanghai, 201203, China.
Xin FuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, 54 Xianlie South Rd, Guangzhou, 510060, China.
Ruobi LiState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, 54 Xianlie South Rd, Guangzhou, 510060, China.
Guisheng ZhongiHuman Institute, ShanghaiTech University, Shanghai, 201210, China. zhongsh@shanghaitech.edu.cn.
Xiaolai ZhouState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, 54 Xianlie South Rd, Guangzhou, 510060, China. zhouxiaolai@gzzoc.com.ORCID http://orcid.org/0000-0002-4531-4658

Funding

Key Research and Development Program of the Ministry of Science and Technology 2022YFF1202901National Natural Science Foundation of China 82171404Natural Science Foundation of Guangdong Province 2023A1515011529Science and Technology Planning Project of Guangzhou City 2023A03J0181, 2024A04J6481the Fundamental Research Funds for the Central Universities 22yklj04the Research Start-up Founds of Sun Yat-sen University Funded Talent[2020]18
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adeno-associated virus (AAV)Age-related macular degeneration (AMD)Gene therapyRetinal degenerative diseasesRetinal pigment epithelium (RPE)

Identifiers

PMID39587629
PMCPMC11590224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.