Evidence map›Paper›PMID 39587203›Full record

ArticleScientific reports2024

New insights into the correlation between bone mineral density and dental caries in NHANES 2011-2016.

Haonan Zhang, Weifeng Jin

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Haonan ZhangSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China.
Weifeng JinSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China. jin_weifeng@126.com.

Funding

Natural Science Foundation of Zhejiang Province LY22H270002, LY24H270007
6 · The paper itself

Abstract

objectivesInvestigate the relationship between bone mineral density (BMD) at various body sites and dental caries. MATERIALS AND

methodsBased on the National Health and Nutrition Examination Survey (NHANES) database from 2011 to 2016, the correlation between BMD at various body sites and the DMFS index among 7044 adults aged 20-59 years was analyzed. Multiple linear regression, restricted cubic splines (RCS), piecewise linear regression, logistic regression, weighted quantile sum regression (WQS) and mediation effects analysis were integrated to explore the relationship between BMD and dental caries.

resultsUnder the linear assumption, except for arm BMD, the BMDs of all other sites are negatively correlated with the DMFS index of dental caries. RCS analysis indicates a U-shaped relationship between head BMD and the DMFS index (p for nonlinear < 0.0001). WQS analysis indicates that mixed BMD is significantly negatively correlated with the DMFS index for dental caries (estimate, - 0.023; 95% CI, - 0.025 ~ - 0.020), and head BMD has the most significant impact on the DMFS index (weight = 91.4%). Simple mediation analysis of the effect of dental caries on BMD levels mediated by inflammation levels showed negative results, suggesting that dental caries may not influence BMD through inflammation levels.

conclusionMonitoring BMD should be combined with appropriate oral healthcare and caries management strategies to effectively address these interconnected health issues, and particular attention should be paid to the monitoring of head BMD.

Indexed as

Bone DensityDental CariesNutrition SurveysAdultDMF IndexFemaleHumansMaleMiddle AgedYoung AdultBMDDental cariesDMFS indexNHANES databaseRegression

Identifiers

PMID39587203
PMCPMC11589834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.