Evidence map›Paper›PMID 39587012›Full record

ReviewCurrent topics in behavioral neurosciences2025

Sex Differences in Neural Circuits Underlying Fear Processing.

Leire Rodríguez Romero, Neha Acharya, Jaime Fabregat Nabás, Ignacio Marín, Raül Andero

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current topics in behavioral neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leire Rodríguez RomeroInstitut de Neurociències, Universistat Autònoma de Barcelona, Barcelona, Spain.
Neha AcharyaInstitut de Neurociències, Universistat Autònoma de Barcelona, Barcelona, Spain.
Jaime Fabregat NabásInstitut de Neurociències, Universistat Autònoma de Barcelona, Barcelona, Spain.
Ignacio MarínInstitut de Neurociències, Universistat Autònoma de Barcelona, Barcelona, Spain.
Raül AnderoDepartament de Psicobiologia i Metodología de les Ciències de la Salut, Universistat Autònoma de Barcelona, Barcelona, Spain. raul.andero@uab.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural circuitry involved in anxiety and fear-related disorders exhibits strong sexual modulation. A limited number of studies integrating female and male data have revealed differences in neural networks, and distinct interconnectivity between these brain areas. Despite the efforts to incorporate female or mixed-sex data, there is compelling evidence that sex, as a biological variable, significantly influences fear processing. This chapter presents primary findings on sex differences in fear circuitry. It is imperative to consider this factor to ensure scientific research's integrity and understand how fear is processed in the central nervous system.

Indexed as

BrainFearNerve NetNeural PathwaysSex CharacteristicsAnimalsFemaleHumansMaleFear conditioningNeural circuitrySex differences

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.