Evidence map›Paper›PMID 39586919›Full record

ArticleInfectious diseases and therapy2025

Etiological, Clinical, and Epidemiological Characteristics of Acute Viral Gastroenteritis in an Adult Population in a Tertiary Level Hospital in Spain.

Sara Herranz-Ulldemolins, Anna Sellarès-Crous, Miriam J Álvarez-Martínez, M Eugenia Valls, Marta Aldea Novo, Anna Vilella Morató, Laura Rodriguez, Mireia Navarro, Roser Vendrell, Josep Barrachina and 2 more

Abstract read
In one paragraph

Article in Infectious diseases and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sara Herranz-Ulldemolins *Department of Preventive Medicine and Epidemiology, Hospital Clínic, Barcelona, Spain.
Anna Sellarès-Crous *Department of Clinical Microbiology, Hospital Clínic, Barcelona, Spain. ansellares@clinic.cat.ORCID http://orcid.org/0000-0001-5644-096X
Miriam J Álvarez-MartínezDepartment of Clinical Microbiology, Hospital Clínic, Barcelona, Spain.
M Eugenia VallsDepartment of Clinical Microbiology, Hospital Clínic, Barcelona, Spain.
Marta Aldea NovoDepartment of Preventive Medicine and Epidemiology, Hospital Clínic, Barcelona, Spain.
Anna Vilella MoratóDepartment of Preventive Medicine and Epidemiology, Hospital Clínic, Barcelona, Spain.
Laura RodriguezDepartment of Clinical Microbiology, Hospital Clínic, Barcelona, Spain.
Mireia NavarroDepartment of Clinical Microbiology, Hospital Clínic, Barcelona, Spain.
Roser VendrellDepartment of Clinical Microbiology, Hospital Clínic, Barcelona, Spain.
Josep BarrachinaDepartment of Clinical Microbiology, Hospital Clínic, Barcelona, Spain.
Miguel J MartínezDepartment of Clinical Microbiology, Hospital Clínic, Barcelona, Spain.
M Ángeles MarcosDepartment of Clinical Microbiology, Hospital Clínic, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute gastroenteritis (AGE) represents a significant global health burden, with enteric viruses being a leading cause of gastroenteritis worldwide. Despite advances in diagnosis and treatment, there are limited data on adults seeking care due to AGE of viral etiology. This study aimed to describe the etiological, clinical, and epidemiological characteristics of viral AGE in adult patients presenting for medical consultation in a tertiary hospital over a 2-year period.

methodsA retrospective cross-sectional study was conducted, with 8886 stool samples from 8356 adult patients presenting acute diarrhea between January 2021 and December 2022. A molecular real-time RT-PCR panel was used to screen for common bacterial, parasitic, and viral pathogens. Clinical and demographic data were collected, and statistical analysis was performed to evaluate possible associations.

resultsEnteric viruses constituted 10.3% (307 cases) of all AGE of known etiology, with norovirus being the predominant pathogen (196, 63.8%), followed by rotavirus (82, 26.7%) and adenovirus (29, 9.4%). The different viruses showed a distinct seasonal predominance. Coinfection with other microorganisms was common. Most cases exhibited a self-limiting course. Mortality and hospitalization rates were high in patients with higher comorbidity indices, mainly in individuals with immunosuppression.

conclusionsViruses are an important cause of acute gastroenteritis in adults presenting for medical consultation. The new multiplex molecular tests with high sensitivity and specificity allow early differential diagnosis in AGE. It is therefore necessary to identify which special populations particularly with higher comorbidity indices, would benefit from the implementation of these techniques, to guide decision-making related to appropriate treatments and avoid unnecessary interventions.

Indexed as

Acute gastroenteritisAdenovirusImmunocompromised patientsNorovirusRotavirusViral enteritis

Identifiers

PMID39586919
PMCPMC11782705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.