Evidence map›Paper›PMID 39586666›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2025

Temperament and executive functioning correlates of ADHD symptom severity during early versus middle childhood.

Virginia Peisch, Erica Ferrara, Gaelle Gourdet, Matthew Zimon, Carissa Mastrangelo, Anne Arnett

Abstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Neural correlates of child temperament: The role of brain network connectivity in psychopathology risk.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Virginia PeischDivision of Developmental Medicine, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0001-6999-0530
Erica FerraraDivision of Developmental Medicine, Boston Children's Hospital, Boston, MA, USA.
Gaelle GourdetDivision of Developmental Medicine, Boston Children's Hospital, Boston, MA, USA.
Matthew ZimonDivision of Developmental Medicine, Boston Children's Hospital, Boston, MA, USA.
Carissa MastrangeloDivision of Developmental Medicine, Boston Children's Hospital, Boston, MA, USA.
Anne ArnettDivision of Developmental Medicine, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0003-1342-0488

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
Neurophysiologically Defined Subtypes of ADHDR00MH116064 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI ARNETT, ANNE BERNARD · 2021 to 2023
$884k
Neurophysiologically Defined Subtypes of ADHDK99MH116064 · NIMH · UNIVERSITY OF WASHINGTON · PI ARNETT, ANNE BERNARD · 2018 to 2019
$255k
NICHD NIH HHS P50 HD105351NIMH NIH HHS K99 MH116064NIMH NIH HHS K99MH116064-01A1NIMH NIH HHS R00 MH116064NIMH NIH HHS R00MH116064-01A1
6 · The paper itself

Abstract

backgroundThis study investigated associations among temperament, executive functioning (EF), and attention-deficit/hyperactivity disorder (ADHD) symptom severity at two developmental stages.

methodsParticipants were 61 4-year-old children and 165 8-11-year-old children (126 ADHD, 39 typically developing [TD]). Caregivers reported on temperament (effortful control [EC], negative affect, and surgency), and ADHD symptoms. Three aspects of EF (working memory, inhibitory control, and processing speed) were measured with neuropsychological tests.

resultsAmong 4-year-olds, variance in ADHD symptom severity was only explained by the temperament variables. EC was not significantly correlated with any of the EFs in this cohort. Among school-aged children, low EC, high surgency, high negative affect, and reduced working memory were associated with greater ADHD symptom severity. EC was significantly and positively correlated with processing speed in the school-aged children.

conclusionsResults are consistent with a neurodevelopmental model of ADHD, wherein dysregulated temperament is associated with ADHD in young children, while both dysregulated temperament and cognitive skills are associated with ADHD in middle childhood. Results could inform the selection of clinical tools for diagnostic evaluation of pediatric ADHD symptoms and clinical follow-up.

Indexed as

Attention Deficit Disorder with HyperactivityChild DevelopmentExecutive FunctionTemperamentChildChild, PreschoolFemaleHumansInhibition, PsychologicalMaleMemory, Short-TermSeverity of Illness IndexAttention‐deficit/hyperactivity disorderdevelopmenteffortful controlexecutive functioningtemperament

Identifiers

PMID39586666
PMCPMC12018159

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.