Evidence map›Paper›PMID 39586561›Full record

ArticleThe journal of pain2025

Neighborhood disadvantage and pain-related experiences in a pain psychology clinic: The mediating roles of pain catastrophizing and pain-related fear.

Fenan S Rassu, Kavya Bhattiprolu, Claudia M Campbell, Stephen T Wegener, Rachel V Aaron

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fenan S RassuJohns Hopkins University, School of Medicine, Department of Physical Medicine and Rehabilitation, USA. Electronic address: frassu1@jhmi.edu.
Kavya BhattiproluJohns Hopkins University, School of Medicine, Department of Physical Medicine and Rehabilitation, USA.
Claudia M CampbellJohns Hopkins University, School of Medicine, Department of Psychiatry & Behavioral Sciences, USA.
Stephen T WegenerJohns Hopkins University, School of Medicine, Department of Physical Medicine and Rehabilitation, USA.
Rachel V AaronJohns Hopkins University, School of Medicine, Department of Physical Medicine and Rehabilitation, USA.

Funding

Optimizing pain-related outcomes following orthopedic trauma: testing novel risk factors and determining the feasibility of a new pain psychology interventionK23HD104934 · NICHD · JOHNS HOPKINS UNIVERSITY · PI Rachel V. Aaron · 2022 to 2026
$756k
Research and Engagement for Advancing Chronic pain Healthcare (REACH)K23MD019351 · NIMHD · JOHNS HOPKINS UNIVERSITY · PI Fenan Rassu · 2024 to 2026
$437k
Mentorship of Junior Investigators on HEAL-SKOAPK24AR081143 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI CAMPBELL, CLAUDIA MICHELLE · 2021 to 2021
$324k
NIAMS NIH HHS K24 AR081143NICHD NIH HHS K23 HD104934NIMHD NIH HHS K23 MD019351
6 · The paper itself

Abstract

This study investigated the relationship between neighborhood disadvantage, measured by the Area Deprivation Index (ADI), and pain-related variables in a pain psychology clinic. We also examined the sequential mediating roles of pain catastrophizing and pain-related fear on these relationships. Participants (N = 509) completed questionnaires assessing usual pain intensity, fatigue, emotional distress, and interference with daily activities. The mean ADI score was 32.57 (SD = 22.65), with scores ranging from 1 to 100. Linear regression analysis, adjusting for age and gender, revealed that higher ADI (i.e., less advantage) was significantly associated with higher scores on pain-related variables (pain intensity: B = 0.026, p < .001; fatigue: B = 0.018, p < .001; emotional distress: B = 0.020, p < .001; interference with daily activities: B = 0.014, p = .006). Sequential mediation analysis revealed pain catastrophizing and pain-related fear mediated these relationships, with significant indirect effects for fatigue (B = 0.001, 95% CI [0.000, 0.002]) and interference with daily activities (B = 0.001, 95% CI [0.001, 0.003]) - but not pain intensity or emotional distress. Pain catastrophizing alone mediated neighborhood disadvantage-pain relationship for all variables. The results suggest that neighborhood disadvantage is associated with higher scores on pain-related experiences and that consistent with the fear avoidance model, pain catastrophizing and pain-related fear may play a role in these relationships for fatigue and interference with daily activities. These findings underscore that neighborhood disadvantage is associated with worse pain-related experiences and highlight the importance of considering neighborhood factors in chronic pain management. PERSPECTIVE: This study identifies potential pathways linking neighborhood disadvantage to chronic pain variables, highlighting the roles of pain catastrophizing and pain-related fear. The findings underscore the need for a holistic approach to pain management that recognizes both individual cognitive-emotional factors and the broader social context in which pain occurs.

Indexed as

CatastrophizationChronic PainFearNeighborhood CharacteristicsPainPsychological DistressActivities of Daily LivingAdultAgedFatigueFemaleHumansMaleMiddle AgedPain MeasurementYoung AdultChronic painNeighborhood disadvantagePain catastrophizingPain-related fearSocial determinants of health

Identifiers

PMID39586561
PMCPMC11807740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.