ArticleJournal of neurosurgery. Case lessons2024
Desmoplastic myxoid tumor of the pineal region, SMARCB1 mutant: illustrative case.
Article in Journal of neurosurgery. Case lessons, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Aggressive clinical behavior of desmoplastic myxoid tumor of the pineal region, SMARCB1-mutant: expanding the biological spectrum of a rare central nervous system neoplasm.Virchows Archiv : an international journal of pathology · 2026Article
- Desmoplastic myxoid tumor, SMARCB1-mutant: a case with late recurrence after long-term follow-up.Free neuropathology · 2026Article
- Pineal Gland Parenchyma Tumors.Advances and technical standards in neurosurgery · 2026Review
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Authors and funding
5 authors.
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Abstract
backgroundDesmoplastic myxoid tumor (DMT) of the pineal region, SMARCB1 mutant is a newly proposed tumor in the 2021 World Health Organization classification of central nervous system tumors. Based on a comprehensive literature review, only 10 cases have been reported so far. OBSERVATIONS: Here, the authors describe a 50-year-old female who presented with sudden headache and dizziness combined with paralysis of upward gaze. Imaging studies showed a pineal region mass with obstructive hydrocephalus. The patient underwent a pineal region tumor resection, and the pathological result confirmed the diagnosis of DMT, SMARCB1 mutant. LESSONS: This case showed a patient with DMT, SMARCB1 mutant with a relatively low Ki-67 proliferation index (less than 1%), clinically combined with typical Parinaud's syndrome. At the same time, the follow-up of this case may provide a better understanding of the prognosis of this specific kind of tumor. https://thejns.org/doi/10.3171/CASE24419.
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