ArticleAnatolian journal of cardiology2024
Radiofrequency Ablation for Patients with Hypertrophic Obstructive Cardiomyopathy Accompanied by Severe Left Ventricular Outflow Tract Obstruction.
Article in Anatolian journal of cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with hypertrophic obstructive cardiomyopathy (HOCM) have few available nonsurgical treatment options. The feasibility of CARTOSound-guided catheter radiofrequency ablation (RFA) has been reported previously; however, relevant data are limited. The objective is to retrospectively evaluate the effectiveness and safety of CARTOSound-guided RFA for patients with HOCM.
methodsThirty-seven patients with successive HOCM accompanied by severe left ventricular outflow tract (LVOT) obstruction underwent CARTOSound-guided RFA were reviewed. The intracardiac echocardiography (ICE) images obtained were merged with the CARTO system to create a shell of the left ventricle. The systolic anterior motion-septal contact area marked from the ICE images was considered the target area for the current delivery of RFA. Follow-up data of the LVOT gradient examined before, 1 month, 6 months, 1 year, and every year after catheter-mediated RFA were accessed.
resultsThe symptoms of 30 patients (81.1%) improved during the follow-up after RFA. The symptoms of all 30 patients were alleviated from the New York Heart Association (NYHA) class IV/III/II to the NYHA class II/I. A sustained and significant gradient reduction was observed in 28 patients (75.7%). The invasive pressure gradient of LVOT was 84.43 ± 27.55 mm Hg before RFA and 42.78 ± 36.38 mm Hg after RFA (P < .001), with a decrease of 41.65 ± 19.72 mm Hg. The median drop in pressure gradient was 36.0% (1.0-67.0%).
conclusionsCatheter-mediated RFA is an effective and safe treatment for patients with HOCM. However, its long-term efficacy and safety should be validated in the future by conducting multicenter clinical trials with large sample sizes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.