Evidence map›Paper›PMID 39585632›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Detection of Serum Antibodies Targeting the Marburg Virus Glycoprotein Using a Multiplex Immunoassay Platform.

Aquena Ball, Teri Ann S Wong, Axel T Lehrer

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aquena BallDepartment of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
Teri Ann S WongDepartment of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
Axel T LehrerDepartment of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA. lehrer@hawaii.edu.

Funding

Preclinical Development of a Thermostable Trivalent Filovirus VaccineR01AI132323 · NIAID · UNIVERSITY OF HAWAII AT MANOA · PI LEHRER, AXEL T · 2017 to 2021
$6.3M
NIAID NIH HHS R01 AI132323
6 · The paper itself

Abstract

Multiplex immunoassays allow for the simultaneous detection of antibody populations targeting multiple antigens in a very sensitive, high-throughput format. This assay has applications in seroprevalence, serodiagnosis, and vaccine assessment with greater sensitivity and dynamic range than standard ELISAs (enzyme-linked immunosorbent assays). Here, we show in detail the methods for multiplex immunoassays to detect IgG to the Marburg virus glycoprotein.

Indexed as

Antibodies, ViralGlycoproteinsMarburgvirusAnimalsEnzyme-Linked Immunosorbent AssayHumansImmunoassayImmunoglobulin GMarburg Virus DiseaseAntibodies, ViralGlycoproteinsImmunoglobulin GHigh-throughput serologyMultiplex immunoassaySerodiagnosisSeroprevalenceViral antigen profiling

Identifiers

PMID39585632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.