Evidence map›Paper›PMID 39585572›Full record

Trial reportClinical rheumatology2025

Electroacupuncture with extensor exercise improves the contraction elastic density of quadriceps in short and long term for knee osteoarthritis.

Bingfeng Xing, Yuanyuan Liu, Xin Zhou, Guanheng He, Wenya Pei, Zhanmou Liang, Jingwen Ruan, Yinghua Duan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bingfeng XingThe First Affiliated Hospital/The First Clinical Medicine School of Guangdong, Pharmaceutical University, Guangzhou, China.
Yuanyuan LiuThe First Affiliated Hospital/The First Clinical Medicine School of Guangdong, Pharmaceutical University, Guangzhou, China.
Xin ZhouThe First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. zhouxin23@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0001-9510-0044
Guanheng HeThe First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Wenya PeiThe First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhanmou LiangThe First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Jingwen RuanThe First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Yinghua DuanThe First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

Funding

Guangdong Provincial Department of Science and Technology 2023A15150122
6 · The paper itself

Abstract

backgroundExtensor training improves the quadriceps contraction intensity of knee osteoarthritis. But the duration of effects is limited. This study aimed to assess whether electroacupuncture (EA) with extensor training (EA + E) has better short-and long-term effects than simple extensor training (E).

methodsFifty-four patients were categorized into EA + E and E groups. Elastic shear wave imaging was employed to ascertain the quadriceps elastic modulus values (EMV) at different time points and extension angles. WOMAC scale was used to measure knee function.

resultsCompared to before EA, the vastus lateralis (VL) EMV with 180° knee extension immediately after EA increased significantly. After 1 month, the vastus medialis (VM) EMV with 180° extension increased and WOMAC scores decreased significantly than immediately after EA. The EMV of the VM and VL of group EA + E increased, and WOMAC scores decreased significantly compared to group E after 1 month. After 6 months, EMV of the VM and VL in EA + E group significantly increased, and WOMAC scores significantly decreased compared to E group.

conclusionsIn short- and long-term, EA with extensor training enhances the contraction strength of the quadriceps and knee function for OA.

trial registrationThis prospective single-center randomized controlled trial was approved by the Review Committee of the First Affiliated Hospital of Sun Yat-sen University (Registration date: 28/02/2023, Ethical Number: [2023] 005; The Clinical trial registration number: ChiCTR2300076651. KEY POINTS: • The contraction strength of the quadriceps femoris muscle in OA was detected with shear wave elastic ultrasound, and electroacupuncture immediately enhanced the contraction strength. • After the completion of electroacupuncture treatment, the quadriceps strength and the function of knee joint in OA can be continuously improved, which will last for 6 months. • In short and long term, electroacupuncture with extensor training has better enhancement of quadriceps contraction strength of and knee function for OA than extention only.

Indexed as

ElectroacupunctureExercise TherapyOsteoarthritis, KneeQuadriceps MuscleAgedFemaleHumansKnee JointMaleMiddle AgedMuscle ContractionMuscle StrengthProspective StudiesTreatment OutcomeElastic shear wave imagingElectroacupuncture (EA)Extensor trainingKnee osteoarthritis (OA)Quadriceps femorisWOMAC scoring scale

Identifiers

PMID39585572
PMCPMC11729210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.