ArticleJapanese journal of radiology2025
Predictive value of pericoronary fat attenuation index for graft occlusion after coronary artery bypass grafting.
Article in Japanese journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Value of Multi-Parameter Combined Application of CZT-SPECT and CCTA in Risk Stratification of Short-Term Myocardial Ischemic Events in Patients with Chronic Coronary Syndromes.Journal of cardiovascular development and disease · 2026Article
- Targeting perivascular adipose tissue in vascular aging: innovative translational strategies for disease prevention and monitoring.Apoptosis : an international journal on programmed cell death · 2026Review
- The Perivascular Fat Attenuation Index: Bridging Inflammation and Cardiovascular Disease Risk.Journal of clinical medicine · 2025Review
- Pericoronary adipose tissue: potential for pathological diagnosis and therapeutic applications.Cardiovascular intervention and therapeutics · 2025Review
- Quantification of water and lipid composition of perivascular adipose tissue using coronary CT angiography: a simulation study.The international journal of cardiovascular imaging · 2025Article
- Roles of perivascular adipose tissue in the pathogenesis of atherosclerosis - an update on recent findings.Frontiers in physiology · 2024Review
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Authors and funding
6 authors.
Funding
Abstract
purposeBased on coronary computed tomography angiography (CCTA), this study aimed to evaluate the predictive value of pericoronary fat attenuation index (FAI) for graft occlusion in patients following coronary artery bypass grafting (CABG). MATERIALS AND
methodsThe clinical and imaging data of 100 patients with coronary artery disease (CAD) who underwent CCTA and subsequently received successful CABG between December 2012 and March 2024 were retrospectively collected. According to the subsequent CCTA evaluation of grafts, they were categorized into occlusion group (n = 27) and patency group (n = 73). Based on CCTA images, FAI of the proximal segment of the three coronary arteries and epicardial adipose tissue (EAT) parameters were measured and compared between the two groups. The Cox regression model was employed to screen the independent predictors of graft occlusion. The predictive model was constructed, and the receiver operating characteristic (ROC) curve was drawn to evaluate the diagnostic performance of the model.
resultsAmong the 100 cases, 74 were males, with a mean age was 62.42 ± 7.57 years. During the 15.50 (5.00, 36.75) months follow-up period, grafting vessel occlusion occurred in 27 patients (27.0%). The right coronary artery (RCA) in occlusion group was -73.36 ± 7.24HU, which was notably higher compared to patency group (-79.93 ± 9.75HU) (P < 0.05). Multivariable Cox regression analysis indicated that RCA FAI (HR = 5.205, 95% CI 1.938-13.979; P = 0.001) was independently correlated with graft occlusion, with an optimal cutoff value of -79.39 HU.RCA FAI added incremental prognostic value beyond clinical characteristics for patients following CABG (AUC 0.784 vs. 0.677, P = 0.027).
conclusionsThe RCA FAI can serve as a crucial predictor for graft occlusion in patients following CABG, enabling early identification of high-risk individuals and facilitating timely and effective intervention measures to enhance patient prognosis.
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