ArticleEJNMMI physics2024
CT radiation dose reduction with tin filter for localisation/characterisation level image quality in PET-CT: a phantom study.
Article in EJNMMI physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- How can children benefit from total-body PET?The British journal of radiology · 2026Review
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4 authors.
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Abstract
backgroundThe tin filter has allowed radiation dose reduction in some standalone diagnostic computed tomography (CT) applications. Yet, 'low-dose' CT scans are commonly used in positron emission tomography (PET)-CT for lesion localisation/characterisation (L/C), with higher noise tolerated. Thus, dose reductions permissible with the tin filter at this image quality level may differ. The aim was to determine the level of CT dose reduction permitted with the tin filter in PET-CT, for comparable image quality to the clinical reference standard (CRS) L/C CT images acquired with standard filtration. MATERIALS AND
methodsA whole-body CT phantom was scanned with standard filtration in CRS protocols, using 120 kV with 20mAs-ref for bone L/C (used in
resultsQuantitative analysis demonstrated dose savings of 50-76% in bone, 27-51% in lung and 8-61% in soft tissue with use of the tin filter at Sn100kV. Qualitative analysis demonstrated dose reductions using Sn100kV in general agreement with the dose reductions indicated by quantitative analysis. Overall, CT dose reductions of around 85% were indicated for NaF bone PET-CT, allowing whole-body CT at just 0.2mSv ED, and a 30-40% CT dose reduction for FDG PET-CT using Sn100kV (1.7-2.0mSv), providing comparable image quality to current CRS images with standard filtration. Sn140kV demonstrated limited value in CT dose reduction.
conclusionsLarge CT dose reductions can be made using the tin filter at Sn100kV, when imaging bone, lung and soft tissue at L/C level CT image quality in PET-CT. As well as reducing the risk of inducing a cancer in later life, such dose reductions may also impact PET-CT practice, such as justifying cross-sectional over planar imaging or justifying PET-CT in younger patients.
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