Evidence map›Paper›PMID 39585455›Full record

ReviewMolecular biology reports2024

The role of mir-7-5p in cancer: function, prognosis, diagnosis, and therapeutic implications.

Zohreh Mirzaei, Tahereh Barati, Amir Ebrahimi, Sima Mansoori Derakhshan, Mahmoud Shekari Khaniani

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Harnessing the Role ofInternational journal of molecular sciences · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zohreh MirzaeiDepartment of Medical Genetics, Tabriz University of Medical Sciences, Tabriz, Iran.
Tahereh BaratiDepartment of Medical Genetics, Tabriz University of Medical Sciences, Tabriz, Iran.
Amir EbrahimiDepartment of Medical Genetics, Tabriz University of Medical Sciences, Tabriz, Iran.
Sima Mansoori DerakhshanDepartment of Medical Genetics, Tabriz University of Medical Sciences, Tabriz, Iran.
Mahmoud Shekari KhanianiDepartment of Medical Genetics, Tabriz University of Medical Sciences, Tabriz, Iran. shekarima@tbzmed.ac.ir.ORCID https://orcid.org/0000-0003-4660-0530

Funding

Tabriz University of Medical Sciences 71847
6 · The paper itself

Abstract

One of the important and conserved microRNAs (miRNAs), miR-7-5p, is involved in several pathological mechanisms, including cell proliferation, apoptosis, migration, and metastasis. Dysregulation of this miRNA's expression is correlated with multiple diseases, especially cancer. Its role as a tumor suppressor has been demonstrated in various types of cancer, such as colorectal cancer, lung cancer, bladder cancer, breast cancer, and glioblastoma. Furthermore, several studies have highlighted the prognostic and diagnostic value of this miRNA, which could be valuable for the diagnosis and treatment of certain disorders. We present an overview of the latest findings regarding miR-7-5p's role in the development of cancer, its action mechanisms, and expression, based on in vivo, in vitro, and human research. Additionally, we discuss the function of miR-7-5p as a prognostic biomarker in cancer and explore its potential as a therapeutic target.

Indexed as

Biomarkers, TumorGene Expression Regulation, NeoplasticMicroRNAsNeoplasmsAnimalsApoptosisCell ProliferationHumansPrognosisBiomarkers, TumorMicroRNAsMIRN7-1 microRNA, humanCancerDiagnosismicroRNAmiR-7-5pPrognosisTherapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.