Evidence map›Paper›PMID 39585385›Full record

ArticleAnnals of hematology2024

The second adult case of NUTM1 fusion-positive B-cell lymphoblastic leukemia: A recurring pattern of poor prognosis.

Xue Chen, Xiaoli Ma, Lili Yuan, Fang Wang, Yang Zhang, Panxiang Cao, Yue Lu, Jiaqi Chen, Xiaosu Zhou, Hongxing Liu

Abstract readCase ReportsLetter
PubMed Publisher
In one paragraph

Article in Annals of hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xue ChenDivision of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, 065201, China.
Xiaoli MaDivision of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, 065201, China.
Lili YuanDivision of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, 065201, China.
Fang WangDivision of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, 065201, China.
Yang ZhangDivision of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, 065201, China.
Panxiang CaoDivision of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, 065201, China.
Yue LuDepartment of Bone Marrow Transplantation, Hebei Yanda Lu Daopei Hospital, Langfang, 065201, China.
Jiaqi ChenDivision of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, 065201, China.
Xiaosu ZhouPrecision Medicine Center, Beijing Lu Daopei Institute of Hematology, Beijing, 100176, China.
Hongxing LiuDivision of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, 065201, China. starliu@pku.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This manuscript reports a rare case of CUX1::NUTM1-positive B-cell lymphoblastic leukemia (B-ALL) in a 25-year-old female patient who experienced early relapse and a poor clinical outcome. Given the rarity of NUTM1 fusion-positive B-ALL in adults, this case contributes to the growing evidence that such cases may present with a more aggressive clinical course compared to the pediatric population. Our findings suggest the need for a re-evaluation of therapeutic strategies in adult patients with this subtype of B-ALL.

Indexed as

Neoplasm ProteinsOncogene Proteins, FusionPrecursor B-Cell Lymphoblastic Leukemia-LymphomaAdultAntineoplastic Combined Chemotherapy ProtocolsFatal OutcomeFemaleHumansNuclear ProteinsPrognosisRecurrenceNeoplasm ProteinsNuclear ProteinsNUTM1 protein, humanOncogene Proteins, Fusion

Identifiers

PMID39585385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.