Evidence map›Paper›PMID 39585129›Full record

ArticleNursing reports (Pavia, Italy)2024

Current Practice and Perspectives on Subcutaneous Immunoglobulin Replacement Therapy in Patients with Primary Antibody Deficiency Among Specialized Nurses in Poland.

Dorota Mizera, Radosław Dziedzic, Anna Drynda, Aleksandra Matyja-Bednarczyk, Agnieszka Padjas, Magdalena Celińska-Löwenhoff, Bogdan Jakieła, Stanisława Bazan-Socha

Abstract read
In one paragraph

Article in Nursing reports (Pavia, Italy), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dorota MizeraJagiellonian University Medical College, Center for Innovative Medical Education, Medyczna 7, 30-688 Kraków, Poland.ORCID 0000-0001-6572-0701
Radosław DziedzicJagiellonian University Medical College, Doctoral School of Medical and Health Sciences, Św. Łazarza 16, 31-530 Kraków, Poland.ORCID 0000-0003-0321-3557
Anna DryndaJagiellonian University Medical College, Students' Scientific Group of Immune Diseases and Hypercoagulation, Jakubowskiego 2, 30-688 Kraków, Poland.ORCID 0009-0009-5556-2637
Aleksandra Matyja-BednarczykJagiellonian University Medical College, Faculty of Medicine, Department of Internal Medicine, Jakubowskiego 2, 30-688 Kraków, Poland.
Agnieszka PadjasJagiellonian University Medical College, Faculty of Medicine, Department of Internal Medicine, Jakubowskiego 2, 30-688 Kraków, Poland.
Magdalena Celińska-LöwenhoffJagiellonian University Medical College, Faculty of Medicine, Department of Internal Medicine, Jakubowskiego 2, 30-688 Kraków, Poland.ORCID 0000-0002-4889-2218
Bogdan JakiełaJagiellonian University Medical College, Faculty of Medicine, Department of Internal Medicine, Jakubowskiego 2, 30-688 Kraków, Poland.ORCID 0000-0003-0444-981X
Stanisława Bazan-SochaJagiellonian University Medical College, Faculty of Medicine, Department of Internal Medicine, Jakubowskiego 2, 30-688 Kraków, Poland.ORCID 0000-0001-9634-0963

Funding

Jagiellonian University Medical College N41/DBS/000687
6 · The paper itself

Abstract

BACKGROUND/

objectivesInborn errors of immunity (IEI) encompass various congenital disorders, resulting in immunity defects and recurrent infections. Home-based subcutaneous immunoglobulin replacement therapy (scIgRT) is the best treatment option for those with primary antibody deficiency (PAD). However, the lack of standardized procedures in patient training remains a challenge. Our study investigates nurses' practice and perspectives, aiming to identify areas for improvement in at-home scIgRT practice.

methodsWe prepared a structured survey regarding scIgRT, including needle choice experience and perception of adverse events, and distributed it among qualified nurses involved in patient training and scIgRT supervising.

resultsWe included 56 nurses with a median age of 50 years. Among them, 67.9% represented adult care providers, while 32.1% supervised IgRT in children. Most respondents (83.9%) used the classic or assisted with hyaluronidase scIgRT preparations. Single-channel needles were administered most commonly (85.7%). The needle length was mostly chosen solely by a nurse (57.1%) or in cooperation with the patient (23.2%). Next, 9 mm and 12 mm needles were used most often (92.9% and 78.6%, respectively). As expected, the 6 mm needle was more frequently applied for children compared to adults (

conclusionsThis study sheds light on scIgRT practice in Poland, emphasizing deficiency in needle selection technique. Future research should focus on standardized training and advanced needle selection procedures on patient outcomes, investigating the correlation between needle strategies and adverse events, as well as the effectiveness of scIgRT.

Indexed as

immunodeficiencyimmunoglobulin replacement therapynursingsurvey

Identifiers

PMID39585129
PMCPMC11587484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.