Evidence map›Paper›PMID 39585100›Full record

ArticlePharmacy (Basel, Switzerland)2024

Assessment of Potential Drug-Drug Interactions of Psycholeptics and Antidepressants in Outpatient Settings.

Iva Marović, Ivana Marinović, Vesna Bačić Vrca, Ivana Samardžić

Abstract read
In one paragraph

Article in Pharmacy (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iva MarovićDepartment of Clinical Pharmacy, University Hospital Dubrava, 10 000 Zagreb, Croatia.
Ivana MarinovićDepartment of Clinical Pharmacy, University Hospital Dubrava, 10 000 Zagreb, Croatia.
Vesna Bačić VrcaFaculty of Pharmacy and Biochemistry, University of Zagreb, 10 000 Zagreb, Croatia.
Ivana SamardžićDepartment of Clinical Pharmacy, University Hospital Dubrava, 10 000 Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mental health is an important segment in preserving overall health and represents a significant public health issue. In modern times, mental health disorders have risen, often requiring complex pharmacotherapy and chronic monitoring. The aim of this research was to determine the prevalence and clinical significance of potential psychotropic drug interactions in outpatient settings and compare the differences in potential drug-drug interaction (pDDIs) exposure with age. The psychotropic drugs included antipsychotics-N05A, anxiolytics-N05B, hypnotics and sedatives-N05C, and antidepressants-N06A. This retrospective study analyzed prescribed pharmacotherapy in 492 outpatients who were treated with at least one psychotropic drug. We determined 1.64 prescribed psychotropic drugs per patient and 2.2 pDDIs that involved psychotropic drugs. In total, 2285 pDDIs were recorded, of which almost half (47.6%) were pDDIs with psychotropic drugs. More prescribed psychotropic drugs were found in patients younger than 65 years, and equal exposure to pDDIs of psychotropic drugs (

Indexed as

drug–drug interactionmental healthoutpatientspharmacistpsychotropic drugs

Identifiers

PMID39585100
PMCPMC11587429

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.