Evidence map›Paper›PMID 39584969›Full record

ArticleMedicines (Basel, Switzerland)2024

Does Ortho-Substitution Enhance Cytotoxic Potencies in a Series of 3,5-Bis(benzylidene)-4-piperidones?

Subhas S Karki, Umashankar Das, Jan Balzarini, Erik De Clercq, Hiroshi Sakagami, Yoshihiro Uesawa, Praveen K Roayapalley, Jonathan R Dimmock

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicines (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Subhas S KarkiCollege of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada.ORCID 0000-0002-5599-3594
Umashankar DasCollege of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada.
Jan BalzariniRega Institute of Medical Research, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.
Erik De ClercqRega Institute of Medical Research, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-2985-8890
Hiroshi SakagamiMekei University Research Institute of Odontology (M-RIO), School of Dentistry, Meikai University, Sakado 350-0238, Saitama, Japan.ORCID 0000-0001-8001-2121
Yoshihiro UesawaDepartment of Medical Molecular Informatics, Meiji Pharmaceutical University, Tokyo 204-858, Japan.ORCID 0000-0002-5773-991X
Praveen K RoayapalleyCollege of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada.ORCID 0000-0003-3712-5790
Jonathan R DimmockCollege of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

4-piperidonesconjugated unsaturated ketonescytotoxicitymolecular modelingortho-effectQSARSARtumor-selective toxicity

Identifiers

PMID39584969
PMCPMC11587156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.