Evidence map›Paper›PMID 39584094›Full record

ArticleHeliyon2024

The impact of site-specific DNA methylation in

Mengmeng Zhu, Qiaoliang Huang, Heng Li, Yujie Zhao, Heming Guo, Tao Wang, Xiaodan Liu, Yun Huang, Ji Hu, Chen Fang and 1 more

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mengmeng ZhuSchool of Basic Medical Sciences, Suzhou medical college of Soochow University, Suzhou, Jiangsu, 215123, China.
Qiaoliang HuangSuzhou Center for Disease Control and Prevention, Suzhou, Jiangsu, 215000, China.
Heng LiSchool of Basic Medical Sciences, Suzhou medical college of Soochow University, Suzhou, Jiangsu, 215123, China.
Yujie ZhaoSchool of Basic Medical Sciences, Suzhou medical college of Soochow University, Suzhou, Jiangsu, 215123, China.
Heming GuoDepartment of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China.
Tao WangDepartment of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China.
Xiaodan LiuDepartment of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China.
Yun HuangDepartment of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China.
Ji HuDepartment of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China.
Chen FangDepartment of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China.
Jian HuangSchool of Basic Medical Sciences, Suzhou medical college of Soochow University, Suzhou, Jiangsu, 215123, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: This study explores the correlation between site-specific methylation levels of the Methods: Thirty patients newly diagnosed with T2DM and 30 healthy controls were selected to determine the CpG methylation levels in the promoter region of the Results: Methylation at multiple CpG sites within the Conclusion: Hypomethylation of specific CpG sites in the promoter region of the

Indexed as

DNA methylationKCNJ11 geneTCF12 transcription factorType 2 diabetes

Identifiers

PMID39584094
PMCPMC11585805

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.