ArticleMethodsX2024
Advancements in dental bioreactor design: A comprehensive approach for application in dentistry.
Article in MethodsX, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The protocol introduces a novel multi-chamber bioreactor tailored for ex-vivo cell culture in dentistry research, emulating the 3D dental environment to propel research in dental applications. Constructed primarily from a polymeric material with a sophisticated 3D design, the bioreactor securely holds teeth structures within sealed chambers, enabling controlled perfusion of culture medium crucial for cell growth through a singular entry and exit point. An integrated electronic system manages flow and pressure, ensuring precise control over environmental conditions. This technology facilitates cell cultivation under conditions closely resembling natural tooth microenvironments, offering opportunities for varied studies from understanding cellular behavior in dental contexts to targeted therapy development. The bioreactor's amalgamation of polymeric components, 3D design, and electronic controls enhances adaptability and accuracy, rendering it a valuable asset in dental research. The report comprehensively delineates the bioreactor's design, operations, and potential applications, showcasing its significant contributions to dental research and regenerative medicine. By amalgamating advanced technologies, this bioreactor emerges as a pivotal tool for investigating cellular processes within dental structures, paving the way for scientific exploration and therapeutic advancements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.