Evidence map›Paper›PMID 39583766›Full record

ArticleYonago acta medica2024

Impact of Lymphocyte/Monocyte Ratio on Outcomes in Patients with Remnant Gastric Cancer After Gastrectomy.

Shota Shimizu, Tomoyuki Matsunaga, Hiroaki Saito, Tomohiro Osaki, Kenji Fukuda, Yoji Fukumoto, Sadamu Takahashi, Kenjiro Taniguchi, Akemi Iwamoto, Hirohiko Kuroda and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Yonago acta medica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shota ShimizuDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
Tomoyuki MatsunagaDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
Hiroaki SaitoDepartment of Surgery, Japanese Red Cross Tottori Hospital, Tottori 680-8517, Japan.
Tomohiro OsakiDepartment of Surgery, Tottori Prefectural Central Hospital, Tottori 680-0901, Japan.
Kenji FukudaDepartment of Surgery, Sanin Rosai Hospital, Yonago 683-8605, Japan.
Yoji FukumotoDivision of Gastroenterology, Matsue City Hospital, Matsue 690-8509, Japan.
Sadamu TakahashiNational Hospital Organization, Hamada Medical Center, Hamada 697-8511, Japan.
Kenjiro TaniguchiDepartment of Surgery, Yonago Medical Center of National Hospital Organization, Yonago 683-0006, Japan.
Akemi IwamotoDivision of Digestive Surgery, Tottori Prefectural Kousei Hospital, Kurayoshi 682-0804, Japan.
Hirohiko KurodaDepartment of Surgery, Japanese Red Cross Masuda Hospital, Masuda 698-8501, Japan.
Kuniyuki KatanoDepartment of Surgery, Nanbu Town National Health Insurance Saihaku Hospital, Nanbu 683-0323, Japan.
Tomohiro TakahashiDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
Yu SakanoDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
Yuji ShishidoDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
Kozo MiyataniDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
Teruhisa SakamotoDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
Yoshiyuki FujiwaraDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The inflammatory response plays a crucial role in tumor development. Inflammatory markers are recognized prognostic factors in many types of cancer, including gastric cancer. However, the correlation between inflammatory markers and prognosis in remnant gastric cancer (RGC) remains unclear. The aim of this study was to evaluate the importance of inflammatory markers as a prognostic factor in patients who underwent gastrectomy for RGC. Methods: This multicenter retrospective study involved 107 patients with RGC who underwent curative gastrectomy at 10 institutions in Japan between January 2000 and December 2016. Both overall survival (OS) and relapse-free survival (RFS) were analyzed. Results: Receiver operating characteristic analyses indicated that the lymphocyte/monocyte ratio (LMR) had a higher area under the curve compared with other potential prognostic factors. Patients were categorized into high- and low LMR groups by the optimal LMR cutoff value. Preoperative LMR was significantly correlated with reconstruction way after the primary surgery (p=0.032) and lymphatic invasion (p=0.046). OS and RFS were significantly worse in the low- vs high LMR groups. Low LMR, T3 or deeper tumor invasion, and low body mass index were independent prognostic factors for OS and RFS. Conclusion: Preoperative low LMR is associated with poor OS and RFS in patients who undergo gastrectomy for RGC.

Indexed as

lymphocyte/monocyte ratioprognosisremnant gastric cancer.

Identifiers

PMID39583766
PMCPMC11584237

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.