Evidence map›Paper›PMID 39583722›Full record

ArticleACS omega2024

Molecular Nanoinformatics Approach Assessing the Coating Oxcarbazepine (OXC) Drug on Silver Nanoparticles.

Norberto de Kássio Vieira Monteiro, Lucas Lima Bezerra, Leonardo P da Silva, Richele Machado

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Norberto de Kássio Vieira MonteiroDepartment of Analytical Chemistry and Physical Chemistry, Science Center, Federal University of Ceará, 60020-181 Fortaleza, CE, Brazil.ORCID https://orcid.org/0000-0002-5847-5733
Lucas Lima BezerraDepartment of Analytical Chemistry and Physical Chemistry, Science Center, Federal University of Ceará, 60020-181 Fortaleza, CE, Brazil.
Leonardo P da SilvaDepartment of Analytical Chemistry and Physical Chemistry, Science Center, Federal University of Ceará, 60020-181 Fortaleza, CE, Brazil.
Richele MachadoChristus University Center, 60160-230 Fortaleza, CE, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver nanoparticles (AgNP) have gained significant attention due to their unique pharmacological properties. These nanoparticles have been found to possess antimicrobial, anti-inflammatory, and antioxidant activities, making them promising candidates for various medical applications. The coating characteristics of oxcarbazepine (OXC), a drug used in epilepsy treatment, on the AgNP icosahedral clusters were investigated using molecular dynamics (MD) simulations and noncovalent interactions (NCI) and Independent Gradient Model (IGM) analysis. We investigated the AgNP coating using OXC drug concentrations of 500, 1000, 1500, 2000, and 2500 ppm. Our results suggested that the OXC drug has a high potential interaction with the AgNP, especially when the concentration increases. Furthermore, it was observed that this interaction occurs mainly through the nitrogen atom (N

Identifiers

PMID39583722
PMCPMC11579947

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.