Evidence map›Paper›PMID 39583660›Full record

ArticleACS omega2024

Identification of Potential Inhibitors of

Maciel Rosas-Cruz, Abraham Madariaga Mazón, Carlos D García-Mejía, Eduardo Hernández-Vázquez, Homero Gómez-Velasco, Eva Jiménez-Faraco, Roberto Sealtiel Farías-Gaytán, Juan A Hermoso, Siseth Martínez-Caballero

Abstract read
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maciel Rosas-CruzInstituto de Química, Universidad Nacional Autonóma de México, A. Universidad 3000, Ciudad Universitaria, CP 04510 Ciudad de México, Mexico.
Abraham Madariaga MazónUnidad Mérida del Instituto de Química, Universidad Nacional Autónoma de México, Km. 5.5 Carr. Sierra Papacal-Chuburna Pto. Sierra Papacal, CP 97302 Yucatán, Mexico.
Carlos D García-MejíaInstituto de Química, Universidad Nacional Autonóma de México, A. Universidad 3000, Ciudad Universitaria, CP 04510 Ciudad de México, Mexico.
Eduardo Hernández-VázquezInstituto de Química, Universidad Nacional Autonóma de México, A. Universidad 3000, Ciudad Universitaria, CP 04510 Ciudad de México, Mexico.
Homero Gómez-VelascoInstituto de Química, Universidad Nacional Autonóma de México, A. Universidad 3000, Ciudad Universitaria, CP 04510 Ciudad de México, Mexico.
Eva Jiménez-FaracoDepartment of Crystallography and structural Biology, Instituto de Química-Física "Blas Cabrera", Consejo Superior de Investigaciones Científicas, E-28006 Madrid, Spain.
Roberto Sealtiel Farías-GaytánInstituto de Química, Universidad Nacional Autonóma de México, A. Universidad 3000, Ciudad Universitaria, CP 04510 Ciudad de México, Mexico.
Juan A HermosoDepartment of Crystallography and structural Biology, Instituto de Química-Física "Blas Cabrera", Consejo Superior de Investigaciones Científicas, E-28006 Madrid, Spain.
Siseth Martínez-CaballeroInstituto de Química, Universidad Nacional Autonóma de México, A. Universidad 3000, Ciudad Universitaria, CP 04510 Ciudad de México, Mexico.ORCID https://orcid.org/0000-0003-4842-8447

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virtual screening is a crucial tool in early stage drug discovery for identifying potential hit candidates. Here, we present an integrated approach that combines theoretical and experimental techniques to identify, for the first time, inhibitors of amidases (Ami1-Ami4) from

Identifiers

PMID39583660
PMCPMC11579945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.