Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Parag Anilkumar ChevliSection on Cardiovascular Medicine Department of Internal Medicine Wake Forest University School of Medicine Winston-Salem North Carolina USA.ORCID https://orcid.org/0000-0002-4084-8175
Christopher L SchaichDepartment of Surgery Hypertension and Vascular Research Center Wake Forest University School of Medicine Winston-Salem North Carolina USA.ORCID https://orcid.org/0000-0002-5302-0828
Alexis C WoodUSDA/ARS Children's Nutrition Research Center Baylor College of Medicine Houston Texas USA.
Luqman A TkSection on Cardiovascular Medicine Department of Internal Medicine Wake Forest University School of Medicine Winston-Salem North Carolina USA.
Vardhmaan JainDivision of Cardiology Department of Medicine Emory University Atlanta Georgia USA.
Margery ConnellyLabCorp Morrisville North Carolina USA.
Suzanne CraftDepartment of Internal Medicine Section on Gerontology and Geriatric Medicine Wake Forest University School of Medicine Winston-Salem North Carolina USA.
Elad ShemeshInstitute of Endocrinology Diabetes, Metabolism and Hypertension Tel Aviv-Sourasky Medical Center Tel Aviv-Yafo Israel.
José A LuchsingerDepartments of Medicine and Epidemiology Columbia University Irving Medical Center New York New York USA.
Kathleen M HaydenDepartment of Social Sciences and Health PolicSy Wake Forest University School of Medicine Winston-Salem North Carolina USA.
Bonnie Colleen SachsDepartment of Social Sciences and Health PolicSy Wake Forest University School of Medicine Winston-Salem North Carolina USA.
Timothy M HughesDepartment of Internal Medicine Section on Gerontology and Geriatric Medicine Wake Forest University School of Medicine Winston-Salem North Carolina USA.
Michael D ShapiroCenter for the Prevention of Cardiovascular Disease Section on Cardiovascular Medicine Wake Forest University School of Medicine Winston-Salem North Carolina USA.ORCID https://orcid.org/0000-0002-9071-3287
Funding
Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD (Renewal)R01AG058969 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Timothy M. Hughes, YONGMEI LIU · 2018 to 2026
$33.4M
Task Area A Core Study Operations.Task Area A shall encompass annual follow-up of cohort members, clinical endpoints ascertainment, study coordination activities, maintenance of the database and biosp75N92020D00001 · NHLBI · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, ROBYN LEAGH · 2020 to 2025
$17.2M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00005 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2020 to 2025
$5.1M
TO EXERCISE OPTION PERIOD ONE (1) FOR TASK AREA A - MESA CORE OPERATIONS, FIELD CENTER.75N92020D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI SIEGEL, JONATHAN H · 2020 to 2025
$4.5M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI PANKOW, JAMES S · 2020 to 2025
$4.4M
The Macrovascular and Microvascular Contributions to Alzheimer's Disease: MESA VASCADR01AG054069 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUGHES, TIMOTHY M. · 2016 to 2020
$3.8M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00003 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI POST, WENDY S · 2020 to 2025
$3.8M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00007 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BERTONI, ALAIN GERALD · 2020 to 2025
$3.5M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00002 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEA, STEVEN J · 2020 to 2025
$3.4M
Cardiac Autonomic Function, Cognitive Performance, and Neurocognitive OutcomesK01AG073581 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SCHAICH, CHRISTOPHER · 2021 to 2024
Introduction: Growing interest centers on the association between circulating ketone bodies (KB) and cognitive function, notably in aging and neurodegenerative diseases. Methods: Associations of plasma KB with incident dementia and cognitive performances were examined among Multi-Ethnic Study of Atherosclerosis (MESA) participants. KB were measured using plasma samples collected following an overnight fasting at Exam 1 (2000-02) and detailed cognitive testing at Exam 5 (2010-2012, Results: Over 16.7 years, a doubling of total KB was associated with a greater risk of incident dementia (hazard ratio [HR]: 1.14 [1.04-1.29]). Higher total KB was associated with worse cognitive performance in the Digit Span test at exam 5 [ Discussion: In a diverse, cardiovascular disease-free population, elevated KB levels were associated with incident dementia and impaired cognitive performance in specific domains. Highlights: A study of ketone bodies (KB) and cognitive performance and incident dementia.Nuclear magnetic resonance (NMR) spectroscopy was used to measure plasma KB at baseline.Doubling of baseline total KB was associated with higher incident dementia.Higher KB was also associated with worse performance on a test of working memory.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Association of circulating ketone bodies with cognitive performance and dementia in the Multi-Ethnic Study of Atherosclerosis (MESA). · full record | OpenQuestion