Evidence map›Paper›PMID 39583627›Full record

ArticleCrystal growth & design2024

Trimesic Acid as a Building Block for Ternary and Quaternary Salts and Salt Cocrystals.

Lamis Alaa Eldin Refat, Marwah Aljohani, Andrea Erxleben

Abstract read
In one paragraph

Article in Crystal growth & design, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lamis Alaa Eldin RefatSchool of Biological and Chemical Sciences, University of Galway, Galway H91TK33, Ireland.ORCID https://orcid.org/0000-0001-5369-0007
Marwah AljohaniDepartment of Chemistry, College of Science, Imam Abdulrahman Bin Faisal University, P.O. Box 76971, Dammam 31441, Saudi Arabia.
Andrea ErxlebenSchool of Biological and Chemical Sciences, University of Galway, Galway H91TK33, Ireland.ORCID https://orcid.org/0000-0002-7309-8972

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the field of cocrystals, the synthon-based design of two-component crystals is well established and the interest is now shifting toward higher order cocrystals as the next challenge. Carboxylic acids form a robust synthon with pyridyl coformers and interact with 2-aminopyrimidines through a pair of strong, charge-assisted hydrogen bonds. In this work we describe the formation of higher order salts and salt cocrystals of trimesic acid using 2,4-diaminopyrimidine (pyrimethamine, trimethoprim) and pyridyl (4,4'-bipyridine, 1,2-di(4-pyridyl)ethylene, 1,3-di(4-pyridyl)propane, 4-phenylpyridine) coformers. We report the single crystal structures of five binary, eight ternary and three quaternary systems with the compositions AB, A

Identifiers

PMID39583627
PMCPMC11583203

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.