ArticleCureus2024
Corneal Endothelial Polymegathism and Pleomorphism Induced by Daily-Wear Soft Contact Lenses.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Corneal and Endothelial Parameters Following Scleral Lens Wear in Post-Keratoplasty Eyes.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Central corneal thickness, corneal endothelial cell density, and morphology in myopic eyes of young Chinese candidates for refractive surgery.Frontiers in ophthalmology · 2026Article
- Relationship between Central Corneal Thickness and Endothelial Cell Density in Individuals with Primary Glaucoma and the General Population Living at High Altitudes.Journal of current ophthalmologyArticle
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCorneal endothelium is responsible for maintaining cornea transparency by pumping fluid out of the stroma to prevent the development of corneal edema which leads to blurring of vision. PURPOSE: The study aims to investigate the corneal endothelial cell density and morphology in young myopic patients wearing disposable soft contact lenses (SLC) using a non-contact specular biomicroscope.
methodsA cross-sectional comparative study was conducted at Qassim University's optometry clinics from February to July 2024 in 100 healthy myopic patients, including 100 eyes wearing disposable soft contact lenses and 100 eyes wearing spectacle correction as control group. Clinical examinations included assessment of refractive error via autorefractometer and visual acuity via projector vision chart. Non-contact specular biomicroscope imaging was used to gather data on corneal endothelial cell density and morphology. Data were analyzed using SPSS v 25 (IBM Corp., Armonk, NY, USA).
resultsA total of 100 healthy myopic patients (200 eyes) participated in this study. Sixty-five (65%) were females and 35 (35%) were males. One hundred eyes wore SCL and 100 eyes were control group. The mean age was 22.14±1.92 years. The mean central corneal thickness (CCT) was 559.54±29.72.91 µm in the SCL group and 539.64±37.55 µm in the control group (p<0.001). The mean endothelial cell density (ECD) was 2628.03±238.66 cells/mm
conclusionWearing disposable soft contact lenses induces significant morphological changes in the corneal endothelium. It increases central corneal thickness and decreases degree of polymegathism and pleomorphism. The longer an individual wears contact lenses, the higher the likelihood decrease in endothelial cell density and polymegathism.
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