Evidence map›Paper›PMID 39583596›Full record

ArticleCureus2024

Neuroregenerative Effects of Radio Electric Asymmetric Conveyer (REAC) Neuroregenerative (RGN-N) Therapy in Pediatric Adrenoleukodystrophy: A Case Report.

Vania Fontani, Arianna Rinaldi, Salvatore Rinaldi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vania FontaniDepartment of Regenerative Medicine, Rinaldi Fontani Institute, Florence, ITA.
Arianna RinaldiDepartment of Adaptive Neuro Psycho Physio Pathology and Neuro Psycho Physical Optimization, Rinaldi Fontani Institute, Florence, ITA.
Salvatore RinaldiDepartment of Regenerative Medicine, Rinaldi Fontani Institute, Florence, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report presents the use of radio electric asymmetric conveyer (REAC) neuroregenerative (RGN-N) therapy in a pediatric patient with adrenoleukodystrophy (ALD), a progressive neurodegenerative disorder with limited therapeutic options. The patient underwent three REAC RGN-N treatment cycles, each lasting 72 hours, with approximately 6-7 hours of daily sessions. An asymmetric conveyor probe (ACP) was positioned along the spine to channel the interaction of the emitted radio electric field with cellular electro-metabolic alterations, promoting progressive bioelectrical restoration. The treatment parameters were pre-set on the REAC device (BENE 110, ASMED, Scandicci, Italy) and could not be altered by the operator, ensuring consistent therapeutic delivery. Significant functional improvements were observed across the motor, cognitive, and swallowing domains, as assessed by standardized scales. This report aligns with preclinical studies on REAC technology's potential for neuroregeneration and suggests REAC RGN-N therapy as a promising adjunctive intervention in ALD management.

Indexed as

adrenoleukodystrophycellular bioelectrical modulationcognitive improvementfunctional recoverymotor function recoveryneuroregenerative treatmentpediatric neurodegenerationrare neurodegenerative disordersreac neuroregenerative therapyspasticity reduction

Identifiers

PMID39583596
PMCPMC11585377

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.