Evidence map›Paper›PMID 39583527›Full record

ArticleCureus2024

Randomized Controlled Trial of Ultrasound-Guided Parasternal Intercostal Nerve Block and Transversus Thoracis Muscle Plane Block for Postoperative Analgesia of Cardiac Surgical Patients.

Sachindra Yadav, Rajesh Raman, Rati Prabha, Dinesh Kaushal, Preeti Yadav, Sarvesh Kumar

Registry-linked trialAbstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07472296 (Sternotomi İle Kardiyak Cerrahi Planlanan Hastalarda Postoperatif Sternotomi Ağrısının Yönetiminde Erektör Spina Plan Blok), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07472296 narecruitingnot on this mapstarted 2025, after this paper: background citation

Sternotomi İle Kardiyak Cerrahi Planlanan Hastalarda Postoperatif Sternotomi Ağrısının Yönetiminde Erektör Spina Plan Blok (ESPB) Ile Yüzeyel Parasternal İnterkostal Plan Bloğu (SPIPB) ve Serratus Anterior Plan Bloğu (SAPB) Kombinasyonunun Karşılaştırılması

TypeinterventionalSponsorUludag UniversityRan2025 to 2026Enrolled50ConditionsPostoperative Pain, Sternotomy Pain, Acute Pain, Cardiac SurgeryArmsErector spinae plane block (ESPB), Superficial Parasternal Intercostal Plane Block (SPIPB), Serratus Anterior Plane Block (SAPB)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sachindra YadavDepartment of Anesthesiology, Sukh Sagar Medical College and Hospital, Jabalpur, IND.
Rajesh RamanDepartment of Anesthesiology, King George's Medical University, Lucknow, IND.
Rati PrabhaDepartment of Anesthesiology, King George's Medical University, Lucknow, IND.
Dinesh KaushalDepartment of Anesthesiology, King George's Medical University, Lucknow, IND.
Preeti YadavDepartment of Anesthesiology, Netaji Subhash Chandra Bose Medical College, Jabalpur, IND.
Sarvesh KumarDepartment of Cardiovascular and Thoracic Surgery, King George's Medical University, Lucknow, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransversus thoracis muscle plane block (TTPB) and parasternal intercostal nerve block (PICNB) inhibit the anterior branches of intercostal nerves and potentially provide adequate analgesia after cardiac surgery. This study aimed to compare these two blocks for a reduction in postoperative opioid consumption after cardiac surgery.

methodsThis randomized, single-blind trial included 60 adult cardiac surgical patients divided into three groups to receive ultrasound-guided TTPB (group T), PICNB (group P), or no block (group C) before surgery. All patients received standard anesthesia with intravenous etomidate, fentanyl, midazolam, and vecuronium. Postoperative fentanyl consumption in the first 24 hours was the primary outcome variable. Secondary outcomes were pain fentanyl consumption in 48 hours, intensity, analgesia duration, heart rate, mean arterial pressure, and complications.

resultsThe groups had similar baseline characteristics. The duration of analgesia was longer, while the intensity of pain and opioid consumption were statistically lower (p<0.01) in groups P and T compared to group C. The differences between groups P and T were not statistically significant. Fentanyl consumption in the first 24 hours was 284.00±37.61 µg, 293.00±35.11 µg, and 383.40±57.21 µg in groups P, T, and C, respectively. Other outcome variables were statistically similar among the groups.

conclusionBoth TTPB and PICNB produce equivalent and satisfactory postoperative analgesia, reducing the postoperative fentanyl use in 24 hours for patients undergoing elective cardiac surgery.

Indexed as

acute post-operative paincardiac surgeryfentanylintercostal nervesregional anesthesiaropivacaine

Identifiers

PMID39583527
PMCPMC11582496

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.