Evidence map›Paper›PMID 39583481›Full record

ArticleCureus2024

Beyond the Norm: Gastroenteritis-Induced Atypical Hemolytic Uremic Syndrome in the Absence of Complement Dysfunction.

Rita Bernardino, Rodrigo Leão, Angela Ghiletchi, Carolina Coelho, Beatriz Sampaio

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rita BernardinoInternal Medicine, Hospital Curry Cabral - Centro Hospitalar Universitário de Lisboa Central, Lisboa, PRT.
Rodrigo LeãoInternal Medicine, NOVA Medical School, Lisboa, PRT.
Angela GhiletchiInternal Medicine, Centro Hospitalar Universitário de Lisboa Central, Lisboa, PRT.
Carolina CoelhoInternal Medicine, Centro Hospitalar Universitário de Lisboa Central, Lisboa, PRT.
Beatriz SampaioInternal Medicine, Centro Hospitalar Universitário de Lisboa Central, Lisboa, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atypical hemolytic uremic syndrome (aHUS) is a complex disorder characterized by thrombotic microangiopathy, typically driven by complement dysregulation. While most cases of aHUS are linked to genetic abnormalities in the complement system, sporadic instances occur without identifiable genetic or complement involvement. This report discusses the case of a 38-year-old woman who developed aHUS following gastroenteritis, marked by acute kidney injury requiring dialysis, yet displayed normal complement levels. This case highlights the diagnostic and management challenges in aHUS when traditional disease markers are absent and emphasizes the importance of tailored therapeutic approaches.

Indexed as

acute kidney injury (aki)atypical hemolytic-uremic syndrome (ahus)gastroenteritisnormal complement systemthrombotic microangiopathy (tma)

Identifiers

PMID39583481
PMCPMC11582949

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.