Evidence map›Paper›PMID 39583431›Full record

ArticleCureus2024

Evaluation of Helicobacter pylori and Small Intestinal Bacterial Overgrowth in Subjects With Rosacea.

Jessie M Nelson, Jason M Rizzo, Rachel K Greene, Kathryn Fahlstrom, Jonathan P Troost, Yolanda R Helfrich, Mio Nakamura

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07122284 (Characterization of Gut Microbiota and Metabolic Profiles in Patients With Helicobacter Pylori Infection and Small Intestinal Bacterial Overgrowth Based on Metagenomic and Metabolomic Analyses), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07122284 completednot on this map

Characterization of Gut Microbiota and Metabolic Profiles in Patients With Helicobacter Pylori Infection and Small Intestinal Bacterial Overgrowth Based on Metagenomic and Metabolomic Analyses

TypeobservationalSponsorZhongshan Hospital (Xiamen), Fudan UniversityRan2024 to 2025Enrolled42ConditionsGut Microbiota, Metabolic Profiles, Helicobacter Pylori Infection, Small Intestinal Bacterial OvergrowthArms13C-Urea Breath Test, Hydrogen-Methane Breath Test
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. The exposomal imprint on rosacea: More than skin deep.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jessie M NelsonDermatology, University of Michigan, Ann Arbor, USA.
Jason M RizzoDermatology, The Woodruff Institute for Dermatology, Bonita Springs, USA.
Rachel K GreeneDermatology, University of Michigan, Ann Arbor, USA.
Kathryn FahlstromDermatology, University of Michigan, Ann Arbor, USA.
Jonathan P TroostBiostatistics, Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, USA.
Yolanda R HelfrichDermatology, University of Michigan, Ann Arbor, USA.
Mio NakamuraDermatology, University of Michigan, Ann Arbor, USA.

Funding

Michigan Institute for Clinical and Health Research (MICHR)UM1TR004404 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Julie C Lumeng · 2023 to 2026
$39.8M
NCATS NIH HHS UM1 TR004404
6 · The paper itself

Abstract

backgroundSystemic abnormalities in the immune system may contribute to rosacea pathogenesis. Several studies have found a higher prevalence of abnormal bacterial growth, such as

objectiveWe aimed to evaluate the prevalence of

methodsThis cross-sectional study evaluated subjects with papulopustular or erythematotelangiectatic rosacea. Subjects with previous or existing gastrointestinal (GI) disease, GI surgery, autoimmune disorders, immunosuppression, or significant comorbidities were excluded. Certain medication use (antibiotics, steroids, GI-modulating medications, anti-inflammatories) required an appropriate washout period. Rosacea history and severity were assessed. Subjects answered questions regarding their rosacea and GI health.

resultsOf 27 subjects, 14.8% (N=4) tested positive for

Indexed as

h. pyloriimmunityinflammationrosaceasibo

Identifiers

PMID39583431
PMCPMC11585968

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.