Evidence map›Paper›PMID 39583341›Full record

ArticleAmerican journal of clinical and experimental immunology2024

Interaction between intratumoral microbiota and neutrophils influences tumor progression.

Mengyuan Hu, Wenshi Hu, Ziyu Zhang

Abstract readEditorial
In one paragraph

Article in American journal of clinical and experimental immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mengyuan HuState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection and School for Radiological and Interdisciplinary Sciences (RAD-X), Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University Suzhou 215123, Jiangsu, China.
Wenshi HuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University Zhenjiang 212013, Jiangsu, China.
Ziyu ZhangState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection and School for Radiological and Interdisciplinary Sciences (RAD-X), Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University Suzhou 215123, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, complex interactions between intratumoral bacteria and neutrophils have been identified as significant factors in tumor occurrence and development. This commentary synthesizes findings from the past five years to explore these interactions. It is observed that during tumor progression, intratumoral bacteria promote neutrophil infiltration and the formation of neutrophil extracellular traps (NETs), which in turn drive tumor development and metastasis. Conversely, infiltrating neutrophils are also capable of slowing tumor progression by limiting the number of intratumoral bacteria. This dual role underscores a potential avenue for improving cancer treatment outcomes.

Indexed as

Intratumoral microbiotaneutrophilstumor progression

Identifiers

PMID39583341
PMCPMC11578806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.