ArticleJournal of conservative dentistry and endodontics2024
Quantitative analysis of antibacterial efficacy of herbal irrigants against endodontic microflora - A clinical study.
Article in Journal of conservative dentistry and endodontics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Antibacterial effectiveness of novel polyherbal gel, chlorhexidine gluconate, and calcium hydroxide as intracanal medicaments in infected root canals using real-time PCR: a randomized controlled trial.Frontiers in dental medicine · 2026Trial
- Post-operative pain in molar teeth with symptomatic apical periodontitis using cryotreated neem extract and cryotreated 2.5% sodium hypochlorite: A randomised double-blinded clinical trial.Bioinformation · 2026Article
- Evaluation of cinnamon zylanicum (true cinnamon) versus ethylenediaminetetraacetic acid smear layer removal ability: A scanning electron microscope study.Journal of conservative dentistry and endodontics · 2025Article
- Development of a loop-mediated isothermal amplification assay for detectingJournal of conservative dentistry and endodontics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: The study aimed to assess the antimicrobial effectiveness of green tea and neem extract compared to sodium hypochlorite (NaOCl) against various root canal microorganisms. Materials and Methods: Thirty patients with pulpal necrosis were selected, providing 60 samples before and after irrigation. Groups were assigned as follows: Group A: 3% NaOCl (control), Group B: green tea, and Group C: neem extract. Samples were collected before and after irrigation in two phases. Samples were collected maintaining a strict sterile condition and stored in buffer solution at -80°C for bacterial-load measurement through real-time Polymerase chain reaction (PCR). Statistical analysis included within-group comparisons using Wilcoxon's test and the paired t-test and inter-group comparisons using the Kruskal-Wallis test with post hoc Dunn's test and one-way analysis of variance with post hoc Tukey's honestly significant difference test ( Results: While no irrigant achieved complete bacterial eradication, all solutions exhibited significant antimicrobial activity postirrigation. NaOCl yielded the most effective results, with green tea nearly comparable, and neem extract demonstrating the lowest efficacy. Conclusions: Herbal irrigants, particularly green tea, can serve as effective alternatives to chemical solutions. However, neem extract proved less effective than both green tea and NaOCl, indicating its inferiority in root canal disinfection.
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Registered trials
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