Evidence map›Paper›PMID 39583064›Full record

ArticleJournal of aging research2024

Exploring the Interplay Between Senescent Osteocytes and Bone Remodeling in Young Rodents.

Insun Song, Pil-Jong Kim, Yong Jun Choi, Yoon-Sok Chung, Soonchul Lee, Jeong-Hwa Baek, Kyung Mi Woo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of aging research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Recent Advances in the Role of Osteocytes in Orthodontic Tooth Movement.International journal of molecular sciences · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Insun SongDental Research Institute, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0000-0001-6418-6359
Pil-Jong KimSchool of Dentistry and Dental Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Yong Jun ChoiDepartment of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
Yoon-Sok ChungDepartment of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
Soonchul LeeDepartment of Orthopaedic Surgery, CHA Bundang Medical Center, CHA University School of Medicine, 59 Yatap-ro, Bundang-gu, Seongnam-si 13496, Republic of Korea.
Jeong-Hwa BaekDental Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Kyung Mi WooDental Research Institute, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0000-0002-2782-1189

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study identifies senescent osteocytes in the femur and tibia of young rodents and explores their role in bone remodeling. The proximity of osteoclasts to senescent osteocytes was observed, which is a new finding. Cultured osteocytes, sorted using a podoplanin antibody in FACS, exhibited osteocytic characteristics and increased senescence-related genes. Senescent osteocytes secreted cytokines associated with senescence, remodeling, and inflammation. Notably, IGF1 and MMP2 were elevated in podoplanin-positive (pdpn

Identifiers

PMID39583064
PMCPMC11585373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.