ArticleChina CDC weekly2024
Phylogeny of Seven Genomes of Monkeypox Virus - Anhui Province, China, 2023.
Article in China CDC weekly, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Article
- Clinical, epidemiological, and genomic evidence on mpox in mainland China, 2022-2025: a scoping review.Frontiers in microbiology · 2026Review
- Genomic and phenotypic insights into the first imported monkeypox virus clade Ia isolate in China, 2025.Frontiers in public health · 2025Article
- Evolutionary epidemiology of the monkeypox virus in Shandong Province during the post-global outbreak era.Frontiers in microbiology · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
What is already known about this topic?: Monkeypox, first identified in Africa in 1958, is a zoonotic disease caused by monkeypox virus (MPXV). Since January 2022, a global outbreak of mpox has spread to over 100 non-endemic countries. As of June 30, 2024, there have been 99,176 confirmed cases and 535 probable cases across 116 countries, resulting in 208 deaths. What is added by this report?: This report presents an analysis of the whole genome sequences of seven MPXVs from Anhui Province. We discovered that, compared to the reference sequence (NC_063383.1), these genomes exhibit 91 nucleotide substitutions and 42 amino acid mutations. They are highly similar to genomes of MPXVs that emerged simultaneously in China, Japan, the Republic of Korea, and Portugal, and are classified within the IIb C.1.1 lineage, with multiple transmission chains and no new branch. What are the implications for public health practice?: The MPXV in Anhui Province has undergone mutations in areas critical for viral replication, transcription, and immune escape, posing a risk of recurrent outbreaks. Therefore, vigilant mutation monitoring of MPXV is imperative.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.