Evidence map›Paper›PMID 39582781›Full record

ArticleMaterials today. Bio2024

"On-demand" nanosystem-integrated microneedles for amplified triple therapy against recalcitrant bacteria and biofilm growth.

Ting Wen, Yiting Zhao, Yanping Fu, Ying Chen, Xiaodie Li, Chaonan Shi, Dongyi Xian, Wanchen Zhao, Dan Yang, Chao Lu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ting WenSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
Yiting ZhaoSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
Yanping FuCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.
Ying ChenCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.
Xiaodie LiCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.
Chaonan ShiCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.
Dongyi XianCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.
Wanchen ZhaoCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.
Dan YangCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.
Chao LuCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.
Chuanbin WuCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.
Xin PanSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
Guilan QuanCollege of Pharmacy, Jinan University, Guangzhou, 511443, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phototherapy has emerged to eradicate recalcitrant bacteria without causing drug resistance, but it is often accompanied by considerable limitations owing to a high tolerance of recalcitrant bacteria to heat and oxidative damage, leading to low efficiency of monotherapy and unwanted side effects. Assuming that employing antimicrobial peptides (AMPs) to disrupt bacterial membranes could reduce bacterial tolerance, a multifunctional "on-demand" nanosystem based on zeolitic imidazolate framework-8 (ZIF-8) with metal ions for intrinsic antibacterial activity was constructed to potently kill methicillin-resistant

Indexed as

Bacterial skin infectionMembranolytic effectMicroneedles“On-demand” releasePhototherapy

Identifiers

PMID39582781
PMCPMC11585702

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.