ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2024
Predictors of Myocardial Fibrosis Detected by CMR in Patients With Idiopathic PVCs.
Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Comprehensive cardiac magnetic resonance imaging in patients with idiopathic premature ventricular contractions: role of feature-tracking strain and T1/T2 mapping in detecting subclinical myocardial dysfunction.Quantitative imaging in medicine and surgery · 2026Article
- Cardiac magnetic resonance imaging in patients referred for premature ventricular contractions: identifying patients most likely to benefit.Frontiers in cardiovascular medicine · 2026Article
- Specific Premature Ventricular Complex Characteristics in Women: Insights from a Patient Cohort.Journal of cardiovascular development and disease · 2025Article
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9 authors.
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Abstract
backgroundPremature ventricular contractions (PVCs) are a frequent electrocardiographic finding in routine medical practice, and 16% of the patients with idiopathic PVCs may have underlying heart disease.
objectiveWe analyzed the correlation between the morphology of the PVCs and the myocardial scarring identified by cardiac magnetic resonance (CMR), together with the impact of late gadolinium enhancement (LGE) on the need for ablation.
methodsNinety-four patients (median age 56 years) with frequent PVCs (> 500 PVCs on 24 h) and a structurally normal heart were referred for comprehensive CMR. The patients were followed for 12 months. Patients were referred for ablation if they were symptomatic in the context of frequent PVCs.
resultsThe prevalence of LGE identified by CMR was higher among males (OR 5.506 (2.092-14.49) p < 0.05), with an age ≥ 50 years (OR 1.047 (1.015-1.08), p < 0.05) and a higher PVC burden (OR 1.922 (1.723-1.976), p < 0.05). Additionally, patients with PVCs with a LBBB inferior axis had four times higher risk of exhibiting LGE (OR 4.09 (1.584-10.565), p < 0.05). In multivariate analysis, age (OR 1.059 (1.019-1.099), p < 0.05) and a LBBB inferior axis (OR 4.605 (1.472-14.404), p < 0.05) were independently associated with the presence of LGE.
conclusionPatients with PVCs and apparently, structurally normal heart present myocardial scarring identified by CMR in 71.23% of cases. PVCs with LBBB inferior axis pattern, age ≥ 50 years and male sex are associated with the presence of LGE on CMR. In multivariate analysis, age and LBBB inferior axis were independently correlated with the presence of LGE.
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