Evidence map›Paper›PMID 39582116›Full record

ArticleDiabetes, obesity & metabolism2025

Comparison of the impact of type 1 and type 2 diabetes on quality of life of families of patients: A UK cross-sectional study.

Rubina Shah, Andrew Y Finlay, Faraz M Ali, Kennedy Otwombe, Stuart J Nixon, Lindsay George, Marc Evans, John R Ingram, Sam Salek

Abstract readComparative Study
In one paragraph

Article in Diabetes, obesity & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rubina ShahDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0001-8158-712X
Andrew Y FinlayDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0003-2143-1646
Faraz M AliDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0002-4184-2023
Kennedy OtwombeStatistics and Data Management Centre, Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-7433-4383
Stuart J NixonMultiple Sclerosis Society, Cardiff, UK.
Lindsay GeorgeDepartment of Diabetes, University Hospital Llandough, Cardiff, UK.ORCID 0009-0000-3411-7256
Marc EvansDepartment of Diabetes, University Hospital Llandough, Cardiff, UK.ORCID 0000-0003-0671-0778
John R IngramDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0002-5257-1142
Sam SalekSchool of Life & Medical Sciences, University of Hertfordshire, Hatfield, UK.ORCID 0000-0002-4612-5699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo measure the impact of type 1 and 2 diabetes mellitus (T1D and T2D) on the QoL of a person's family members/partner and assess if there is any difference in family impact.

methodsA cross-sectional study, recruited online through patient support groups, involved UK family members/partners of people with diabetes completing the Family Reported Outcome Measure-16 (FROM-16).

resultsTwo hundred and sixty-one family members/partners (mean age = 57.9 years, SD = 13.8; females = 68.2%) of people with diabetes (mean age = 57.7, SD = 20.6; females = 38.3%; T1D n = 100; T2D n = 161) completed the FROM-16. The overall FROM-16 mean score was 10.47, SD = 7.8, suggesting a moderate effect on the QoL of family members of people with diabetes. A quarter (24.5%) of family members experienced a 'very large effect' or 'extremely large effect' on their QoL. The family impact of T1D (mean FROM-16 = 12.61, SD = 7.9) was greater than that of T2D (mean = 9.15, SD = 7.5, p < 0.01), with being 'female' and 'parents of children and adolescents' rendered as significant predictors of greater impact. Family members of T2D had a lower risk of experiencing a high family impact (FROM-16 score >16) compared with T1D (RR 0.561, 95% CI 0.371-0.849).

conclusionsCompared to T2D, family members of T1D experience a greater impact on their QoL, particularly those caring for children and adolescents. These findings have clinical and resource implications, indicating a need to assess this impact as a part of routine diabetes care to support impacted family members. The FROM-16 could assess this impact in routine practice and further facilitate referral of family members to appropriate support services.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2FamilyQuality of LifeAdolescentAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesUnited Kingdomdiabetesdiabetes secondary burdenfamily impactfamily members/partnersFamily Reported Outcome Measure‐16FROM‐16quality of lifetype 1 diabetes mellitustype 2 diabetes mellitus

Identifiers

PMID39582116
PMCPMC11701181

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.